Nancy W Glynn

Contributions to Public Health

• I am tenured and have been the director of Master’s Degree Programs in the Department of Epidemiology since 2012. As an established physical activity epidemiologist with nearly 30 years of experience, my research program focuses on the measurement of fatigability, physical activity, fitness, and physical function in older adults.
  • Glynn NW, Qiao YS. Measuring and Understanding the Health Impact of Greater Fatigability in Older Adults: A Call to Action and Opportunities. Fatigue. 2023;11(2-4):188-201. doi: 10.1080/21641846.2023.2252612. Epub 2023 Sep 4. PMID: 38074079; PMCID: PMC10707490. 
  • Glynn NW, Gmelin T, Renner SW, Qiao YS, Boudreau RM, Feitosa MF, Wojczynski MK, Cosentino S, Andersen SL, Christensen K, Newman AB. Perceived Physical Fatigability Predicts All-Cause Mortality in Older Adults. J Gerontol A Biol Sci Med Sci. 2022 Apr 1;77(4):837-841. doi: 10.1093/gerona/glab374. PMID: 34908118; PMCID: PMC8974332.
• I have made landmark scientific contributions by developing and validating the Pittsburgh Fatigability Scale (PFS) and Pittsburgh Performance Fatigability Index (PPFI). The validated PFS, a unique assessment tool translated into 20 languages, has been implemented in many large-scale studies worldwide. The PPFI is a patent-pending, validated novel accelerometry-derived measurement of cadence decline during walking tasks.
  • Glynn NW, Santanasto AJ, Simonsick EM, Boudreau RM, Beach SR, Schulz R, Newman AB. The Pittsburgh Fatigability Scale for older adults: Development and validation. J Am Geriatr Soc. 2015 Jan; 63(1):130-5. PMCID: PMC4971882.
  • Qiao YS, Harezlak J, Moored KD, Urbanek JK, Boudreau RM, Toto PE, Hawkins M, Santanasto AJ, Schrack JA, Simonsick EM, Glynn NW. Development of a Novel Accelerometry-Based Performance Fatigability Measure for Older Adults. Med Sci Sports Exerc. 2022 Oct 1;54(10):1782-1793. doi: 10.1249/MSS.0000000000002966. Epub 2022 Jun 24. PMID: 35763596; PMCID: PMC9481701
• I am also a leader in the physical activity sphere, where my work centers on identifying optimal measurement methods by applying innovative techniques using raw accelerometry. My long-term expertise in measuring and interpreting data from objective wearable devices has led to major collaborations on NIH-funded studies and the establishment of the Glynn Accelerometry Reading Center.
  • Urbanek JK, Zipunnikov V, Harris T, Crainiceanu C, Harezlak J, Glynn NW. Validation of gait characteristics extracted from raw accelerometry during walking against measures of physical function, mobility, fatigability, and fitness.  The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences. 2018 Apr 17;73(5):676-681. doi: 10.1093/gerona/glx174. PMID: 28958000; PMCID: PMC5905654.
  • Qiao YS, Blackwell TL, Cawthon PM, Coen PM, Cummings SR, Distefano G, Farsijani S, Forman DE, Goodpaster BH, Kritchevsky SB, Mau T, Toledo FGS, Newman AB, Glynn NW. Associations of accelerometry-measured and self-reported physical activity and sedentary behavior with skeletal muscle energetics: The Study of Muscle, Mobility and Aging (SOMMA). J Sport Health Sci. 2024 Sep;13(5):621-630. doi: 10.1016/j.jshs.2024.02.001. Epub 2024 Feb 9. PMID: 38341136; PMCID: PMC11282341.
  • Werkmann V, Glynn NW, Harezlak J. Extracting actigraphy-based walking features with structured functional principal components. Physiol Meas. 2024 Aug 2;45(8):085001. doi: 10.1088/1361-6579/ad65b2. PMID: 39029489; PMCID: PMC11326485.
     
• As a mentor, in my role as director of master’s degree programs I serve as the primary academic advisor for 70-90 students annually. Additionally, I am currently the doctoral advisor/dissertation chair for 4 students. I have provided extensive training in design, methodology, analysis, and reporting of results, as evidenced by the 75+ theses, essays, and dissertations authored by my mentees under my direction.
  • *Gay EL, Coen PM, Harrison S, Garcia RE, Qiao YS, Goodpaster BH, Forman DE, Toledo FGS, Distefano G, Kramer PA, Ramos SV, Molina AJA, Nicklas BJ, Cummings SR, Cawthon PM, Hepple RT, Newman AB, Glynn NW. Sex differences in the association between skeletal muscle energetics and perceived physical fatigability: the Study of Muscle, Mobility and Aging (SOMMA). Geroscience. 2024 Oct 22. doi: 10.1007/s11357-024-01373-z. Epub ahead of print. PMID: 39436549.
    *Garcia RE, Blackwell TL, Forman DE, Coen PM, Nicklas BJ, Qiao YS, Cawthon PM, Toledo FGS, Goodpaster BH, Cummings SR, Newman AB, Glynn NW. Role of Walking Energetics and Perceived Fatigability Differs by Gait Speed: The Study of Muscle, Mobility and Aging (SOMMA). J Gerontol A Biol Sci Med Sci. 2024 Sep 1;79(9):glae187. doi: 10.1093/gerona/glae187. PMID: 39066507; PMCID: PMC11341985.
• I am committed to inclusive excellence and diversity in the rigorous training of future epidemiologists as they transition into research careers consistent with their interests and skills, including in academic positions. I highly value diversity in my trainees as it provides innovative, balanced, and informed perspectives that enhance scientific productivity and fosters the growth of my team and the field.