Anne B Newman, MD, MPH

Departmental Administrator
Donna Bushey
E-mail: dlb22@pitt.edu
Primary Phone: 412-624-3056

Research Administrator
Michelle Utz-Kiley
E-mail: meu2@pitt.edu
Primary Phone: 412-383-1302

Dr. Newman's research focuses on aging, including the determinants of physical and cognitive function as well as successful aging and longevity. She has special expertise in the study of cardiovascular disease and aging and body composition, sarcopenia, and physical functioning. She is presently the Principal Investigator (PI) of several long term cohort studies and clinical trials in older adults funded by the National Institute on Aging (NIA).

Dr. Newman is professor and chair of the Department of Epidemiology in the Graduate School of Public Health at the University of Pittsburgh with a secondary appointment in the Department of Medicine and with the Clinical and Translational Science Institute (CTSI) at the University of Pittsburgh. She was appointed to the Katherine M. Detre Endowed Chair of Population Health Science in the Graduate School of Public Health in June, 2014. Dr. Newman is an elected member of the American Epidemiology Society and the Delta Omega Honor Society in Public Health. Dr. Newman is certified by the American Board of Internal Medicine with added qualifications in geriatric medicine. She directs the Center for Aging and Population Health in the Graduate School of Public Health which includes a CDC Prevention Research Center and an NIA National Service Award for training epidemiology doctoral fellows in the Epidemiology of Aging. She also serves as co-PI for the NIA funded Older Americans Independence Center in the Department of Medicine.

1987 | University of Pittsburgh, Pittsburgh, PA | MPH, Public Health
1985-1987 | Presbyterian University Hospital, Pittsburgh, PA | Fellowship Geriatric Medicine
1982-1985 | Presbyterian University Hospital, Pittsburgh, PA | Internship & Residency
1982 | University of Pittsburgh, Pittsburgh, PA | MD, Medicine
1978 | University of Pittsburgh, Pittsburgh, PA | BS, Biology

EPI 2980 | Biology and Physiology of Aging
EPI 2900 | Advanced Epidemiology of Aging
EPI 2920 | Writing in Epidemiology: Manuscripts and Grants
EPI 2260 | Epidemiological Basis for Disease Control

Dr. Newman serves as Associate Editor of the Journal of Gerontology: Medical Science and on the editorial boards of several other journals. She has long-standing service to NIH for grant review as a member of the Neurological Musculoskeletal and Aging Epidemiology Committee and as a member of several NIH monitoring boards for large cohort studies. She recently served on an Institute of Medicine’s Panel on the Adequacy of Evidence for Physical Guidelines, addressing guidelines for older adults.

• Subclinical atherosclerosis: associations with aging, disability and frailty
• Sarcopenia and disability
• Healthy aging and longevity

Principal Investigator

• Lifestyle and Independence for the Elderly (LIFE) (2009-2016) NIA
• ASPirin to Reduce Events in the Elderly (ASPREE) (2009-2016) NIA
• The Long Life Family Study (2004-2019) NIA
• The CHS All Stars Study (Exceptional Aging:12 Year Trajectories to function) (2004-2016) NIA
• The Health, Aging and Body Composition Study (1996-2011) NIA
• Center for Aging and Population Health – Prevention Research Center (CAPH-PRC) (2010-2015) CDC

Co-Principal Investigator

• University of Pittsburgh Clinical Center for the Osteoarthritis Institute (2002-2013) NIAMS
• Cardiovascular Health Study (CHS 1988-) NHLBI
• Peripheral Nerve Function Decline in an Aged Cohort (2007-2012)
• Brain Anatomical Correlates of Mobility Control in Oldest Old (2007-2012)
• Study of Osteoporotic Fractures (SOF) – Pittsburgh Clinical Center – Renewal (2011-2016) NIA
• Study of Osteoporotic Fractures in Men (MrOS) (2103-2018) NIA
• Pittsburgh Older Americans Independence Center (2004-2014) NIA

Other

• Training in the Epidemiology of Aging (Director) (2008-2010) NIH/NIA

1. Santanasto AJ, Glynn NW, Jubrias SA, Conley KE, Boudreau RM, Amati F, Mackey DC, Simonsick EM, Strotmeyer ES, Coen PM, Goodpaster BH, Newman AB. Skeletal Muscle Mitochondrial Function and Fatigability in Older Adults. J Gerontol A Biol Sci Med Sci. 2015 Nov;70(11):1379-85. doi: 10.1093/gerona/glu134. Epub 2014 Aug 28. PMID: 25167867; PMCID: PMC4612379.
2. Katzman SM, Strotmeyer ES, Nalls MA, Zhao Y, Mooney S, Schork N, Newman AB, Harris TB, Yaffe K, Cummings SR, Liu Y, Tranah GJ; Health, Aging, and Body Composition Study. Mitochondrial DNA Sequence Variation Associated With Peripheral Nerve Function in the Elderly. J Gerontol A Biol Sci Med Sci. 2015 Nov;70(11):1400-8. doi: 10.1093/gerona/glu175. Epub 2014 Nov 13. PMID: 25394619; PMCID: PMC4612380.
3. Åsvold BO, Vatten LJ, Bjøro T, Bauer DC, Bremner A, Cappola AR, Ceresini G, den Elzen WP, Ferrucci L, Franco OH, Franklyn JA, Gussekloo J, Iervasi G, Imaizumi M, Kearney PM, Khaw KT, Maciel RM, Newman AB, Peeters RP, Psaty BM, Razvi S, Sgarbi JA, Stott DJ, Trompet S, Vanderpump MP, Völzke H, Walsh JP, Westendorp RG, Rodondi N; Thyroid Studies Collaboration. Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts. JAMA Intern Med. 2015 Jun;175(6):1037-47. doi: 10.1001/jamainternmed.2015.0930. PMID: 25893284; PMCID: PMC4732559.
4. Marcum ZA, Perera S, Newman AB, Thorpe JM, Switzer GE, Gray SL, Simonsick EM, Shorr RI, Bauer DC, Castle NG, Studenski SA, Hanlon JT; Health ABC Study. Antihypertensive Use and Recurrent Falls in Community-Dwelling Older Adults: Findings From the Health ABC Study. J Gerontol A Biol Sci Med Sci. 2015 Dec;70(12):1562-8. doi: 10.1093/gerona/glv095. Epub 2015 Aug 11. PMID: 26265732; PMCID: PMC4643613.
5. Reinders I, Murphy RA, Martin KR, Brouwer IA, Visser M, White DK, Newman AB, Houston DK, Kanaya AM, Nagin DS, Harris TB; Health, Aging and Body Composition Study. Body Mass Index Trajectories in Relation to Change in Lean Mass and Physical Function: The Health, Aging and Body Composition Study. J Am Geriatr Soc. 2015 Aug;63(8):1615-21. doi: 10.1111/jgs.13524. PMID: 26289686; PMCID: PMC4785850.
6. Perera S, Patel KV, Rosano C, Rubin SM, Satterfield S, Harris T, Ensrud K, Orwoll E, Lee CG, Chandler JM, Newman AB, Cauley JA, Guralnik JM, Ferrucci L, Studenski SA. Gait Speed Predicts Incident Disability: A Pooled Analysis. J Gerontol A Biol Sci Med Sci. 2016 Jan;71(1):63-71. doi: 10.1093/gerona/glv126. Epub 2015 Aug 22. PMID: 26297942; PMCID: PMC4715231.
7. Corrales-Medina VF, Taljaard M, Yende S, Kronmal R, Dwivedi G, Newman AB, Elkind MS, Lyles MF, Chirinos JA. Intermediate and long-term risk of new-onset heart failure after hospitalization for pneumonia in elderly adults. Am Heart J. 2015 Aug;170(2):306-312.e6. doi: 10.1016/j.ahj.2015.04.028. Epub 2015 May 2. PMID: 26299228; PMCID: PMC4548825.
8. Sink KM, Espeland MA, Castro CM, Church T, Cohen R, Dodson JA, Guralnik J, Hendrie HC, Jennings J, Katula J, Lopez OL, McDermott MM, Pahor M, Reid KF, Rushing J, Verghese J, Rapp S, Williamson JD; LIFE Study Investigators. Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial. JAMA. 2015 Aug 25;314(8):781-90. doi: 10.1001/jama.2015.9617. PMID: 26305648;
9. Chalhoub D, Cawthon PM, Ensrud KE, Stefanick ML, Kado DM, Boudreau R, Greenspan S, Newman AB, Zmuda J, Orwoll ES, Cauley JA; Osteoporotic Fractures in Men Study Research Group. Risk of Nonspine Fractures in Older Adults with Sarcopenia, Low Bone Mass, or Both. J Am Geriatr Soc. 2015 Sep;63(9):1733-40. doi: 10.1111/jgs.13605. Epub 2015 Aug 27. PMID: 26310882; PMCID: PMC4625906.
10. Hall MH, Smagula SF, Boudreau RM, Ayonayon HN, Goldman SE, Harris TB, Naydeck BL, Rubin SM, Samuelsson L, Satterfield S, Stone KL, Visser M, Newman AB. Association between sleep duration and mortality is mediated by markers of inflammation and health in older adults: the Health, Aging and Body Composition Study. Sleep. 2015 Feb 1;38(2):189-95. doi: 10.5665/sleep.4394. PMID: 25348127 [PubMed - indexed for MEDLINE] Free PMC Article PMCID: PMC4288599.
11. Ashar FN, Moes A, Moore AZ, Grove ML, Chaves PH, Coresh J, Newman AB, Matteini AM, Bandeen-Roche K, Boerwinkle E, Walston JD, Arking DE. Association of mitochondrial DNA levels with frailty and all-cause mortality. J Mol Med (Berl). 2015 Feb;93(2):177-86. doi: 10.1007/s00109-014-1233-3. Epub 2014 Dec 4. PMID: 25471480 [PubMed - indexed for MEDLINE] PMCID: PMC4319988.
12. Minster RL, Sanders JL, Singh J, Kammerer CM, Barmada MM, Matteini AM, Zhang Q, Wojczynski MK, Daw EW, Brody JA, Arnold AM, Lunetta KL, Murabito JM, Christensen K, Perls TT, Province MA, Newman AB. Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index. J Gerontol A Biol Sci Med Sci. 2015 Aug;70(8):1003-8. doi: 10.1093/gerona/glv006. Epub 2015 Mar 10. PMID: 25758594; PMCID: PMC4506316.
13. Genther DJ, Betz J, Pratt S, Martin KR, Harris TB, Satterfield S, Bauer DC, Newman AB, Simonsick EM, Lin FR; Health, Aging and Body Composition Study. Association Between Hearing Impairment and Risk of Hospitalization in Older Adults. J Am Geriatr Soc. 2015 Jun;63(6):1146-52. doi: 10.1111/jgs.13456. Epub 2015 Jun 11. PMID: 26096388; PMCID: PMC4477278.
14. Tranah GJ, Yaffe K, Katzman SM, Lam ET, Pawlikowska L, Kwok PY, Schork NJ, Manini TM, Kritchevsky S, Thomas F, Newman AB, Harris TB, Coleman AL, Gorin MB, Helzner EP, Rowbotham MC, Browner WS, Cummings SR; Health, Aging and Body Composition Study. Mitochondrial DNA Heteroplasmy Associations With Neurosensory and Mobility Function in Elderly Adults. 2015;70(11):1418-1424. doi: 10.1093/gerona/glv097. PMID: 26328603; PMCID: PMC4612388.
15. Kim DH, Grodstein F, Newman AB, Chaves PH, Odden MC, Klein R, Sarnak MJ, Lipsitz LA. Microvascular and Macrovascular Abnormalities and Cognitive and Physical Function in Older Adults: Cardiovascular Health Study. J Am Geriatr Soc. 2015 Sep;63(9):1886-93. doi: 10.1111/jgs.13594. Epub 2015 Sep 4. PMID: 26338279; PMCID: PMC4578971.
16. Lange-Maia BS, Newman AB, Cauley JA, Boudreau RM, Jakicic JM, Caserotti P, Glynn NW, Harris TB, Kritchevsky SB, Schwartz AV, Satterfield S, Simonsick EM, Vinik AI, Zivkovic S, Strotmeyer ES; Health, Aging, and Body Composition Study. Sensorimotor Peripheral Nerve Function and the Longitudinal Relationship with Endurance Walking in the Health, Aging and Body Composition Study. Arch Phys Med Rehabil. 2016 Jan;97(1):45-52. doi: 10.1016/j.apmr.2015.08.423. PMID: 26343170; PMCID: PMC4696894.
17. Semba RD, Ferrucci L, Sun K, Simonsick E, Turner R, Miljkovic I, Harris T, Schwartz AV, Asao K, Kritchevsky S, Newman AB; Health ABC Study. Low Plasma Klotho Concentrations and Decline of Knee Strength in Older Adults. J Gerontol A Biol Sci Med Sci. 2016 Jan;71(1):103-8. doi: 10.1093/gerona/glv077. PMID: 26359247; PMCID: PMC4706099.
18. Aronis KN, Wang N, Phillips CL, Benjamin EJ, Marcus GM, Newman AB, Rodondi N, Satterfield S, Harris TB, Magnani JW; Health ABC study. Associations of obesity and body fat distribution with incident atrial fibrillation in the biracial health aging and body composition cohort of older adults. Am Heart J. 2015 Sep;170(3):498-505.e2. doi: 10.1016/j.ahj.2015.06.007. Epub 2015 Jun 14. PMID: 26385033; PMCID: PMC4575766.
19. Izano M, Wei EK, Tai C, Swede H, Gregorich S, Harris TB, Klepin H, Satterfield S, Murphy R, Newman AB, Rubin SM, Braithwaite D; for the Health ABC study. Chronic Inflammation and Risk of Colorectal and Other Obesity-Related Cancers: The Health, Aging, and Body Composition Study. Int J Cancer. 2016 Mar 1;138(5):1118-28. doi: 10.1002/ijc.29868. Epub 2015 Oct 19. PMID: 26413860;
20. Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, Esko T, Johnson AD, Elks CE, Franceschini N, He C, Altmaier E, Brody JA, Franke LL, Huffman JE, Keller MF, McArdle PF, Nutile T, Porcu E, Robino A, Rose LM, Schick UM, Smith JA, Teumer A, Traglia M, Vuckovic D, Yao J, Zhao W, Albrecht E, Amin N, Corre T, Hottenga JJ, Mangino M, Smith AV, Tanaka T, Abecasis GR, Andrulis IL, Anton-Culver H, Antoniou AC, Arndt V, Arnold AM, Barbieri C, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bernstein L, Bielinski SJ, Blomqvist C, Boerwinkle E, Bogdanova NV, Bojesen SE, Bolla MK, Borresen-Dale AL, Boutin TS, Brauch H, Brenner H, Brüning T, Burwinkel B, Campbell A, Campbell H, Chanock SJ, Chapman JR, Chen YI, Chenevix-Trench G, Couch FJ, Coviello AD, Cox A, Czene K, Darabi H, De Vivo I, Demerath EW, Dennis J, Devilee P, Dörk T, Dos-Santos-Silva I, Dunning AM, Eicher JD, Fasching PA, Faul JD, Figueroa J, Flesch-Janys D, Gandin I, Garcia ME, García-Closas M, Giles GG, Girotto GG, Goldberg MS, González-Neira A, Goodarzi MO, Grove ML, Gudbjartsson DF, Guénel P, Guo X, Haiman CA, Hall P, Hamann U, Henderson BE, Hocking LJ, Hofman A, Homuth G, Hooning MJ, Hopper JL, Hu FB, Huang J, Humphreys K, Hunter DJ, Jakubowska A, Jones SE, Kabisch M, Karasik D, Knight JA, Kolcic I, Kooperberg C, Kosma VM, Kriebel J, Kristensen V, Lambrechts D, Langenberg C, Li J, Li X, Lindström S, Liu Y, Luan J, Lubinski J, Mägi R, Mannermaa A, Manz J, Margolin S, Marten J, Martin NG, Masciullo C, Meindl A, Michailidou K, Mihailov E, Milani L, Milne RL, Müller-Nurasyid M, Nalls M, Neale BM, Nevanlinna H, Neven P, Newman AB, Nordestgaard BG, Olson JE, Padmanabhan S, Peterlongo P, Peters U, Petersmann A, Peto J, Pharoah PD, Pirastu NN, Pirie A, Pistis G, Polasek O, Porteous D, Psaty BM, Pylkäs K, Radice P, Raffel LJ, Rivadeneira F, Rudan I, Rudolph A, Ruggiero D, Sala CF, Sanna S, Sawyer EJ, Schlessinger D, Schmidt MK, Schmidt F, Schmutzler RK, Schoemaker MJ, Scott RA, Seynaeve CM, Simard J, Sorice R, Southey MC, Stöckl D, Strauch K, Swerdlow A, Taylor KD, Thorsteinsdottir U, Toland AE, Tomlinson I, Truong T, Tryggvadottir L, Turner ST, Vozzi D, Wang Q, Wellons M, Willemsen G, Wilson JF, Winqvist R, Wolffenbuttel BB, Wright AF, Yannoukakos D, Zemunik T, Zheng W, Zygmunt M, Bergmann S, Boomsma DI, Buring JE, Ferrucci L, Montgomery GW, Gudnason V, Spector TD, van Duijn CM, Alizadeh BZ, Ciullo M, Crisponi L, Easton DF, Gasparini PP, Gieger C, Harris TB, Hayward C, Kardia SL, Kraft P, McKnight B, Metspalu A, Morrison AC, Reiner AP, Ridker PM, Rotter JI, Toniolo D, Uitterlinden AG, Ulivi S, Völzke H, Wareham NJ, Weir DR, Yerges-Armstrong LM; PRACTICAL Consortium; kConFab Investigators; AOCS Investigators; Generation Scotland; EPIC-InterAct Consortium; LifeLines Cohort Study, Price AL, Stefansson K, Visser JA, Ong KK, Chang-Claude J, Murabito JM, Perry JR, Murray A. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nat Genet. 2015 Nov;47(11):1294-303. doi: 10.1038/ng.3412. Epub 2015 Sep 28. PMID: 26414677; PMCID: PMC4661791.
21. Fitzgerald JD, Johnson L, Hire DG, Ambrosius WT, Anton SD, Dodson JA, Marsh AP, McDermott MM, Nocera JR, Tudor-Locke C, White DK, Yank V, Pahor M, Manini TM, Buford TW; LIFE Study Research Group. Association of objectively measured physical activity with cardiovascular risk in mobility-limited older adults. J Am Heart Assoc. 2015 Feb 18;4(2). pii: e001288. doi: 10.1161/JAHA.114.001288. PMID: 25696062; PMCID: PMC4345863.
22. Chaker L, Baumgartner C, den Elzen WP, Ikram MA, Blum MR, Collet TH, Bakker SJ, Dehghan A, Drechsler C, Luben RN, Hofman A, Portegies ML, Medici M, Iervasi G, Stott DJ, Ford I, Bremner A, Wanner C, Ferrucci L, Newman AB, Dullaart RP, Sgarbi JA, Ceresini G, Maciel RM, Westendorp RG, Jukema JW, Imaizumi M, Franklyn JA, Bauer DC, Walsh JP, Razvi S, Khaw KT, Cappola AR, Völzke H, Franco OH, Gussekloo J, Rodondi N, Peeters RP; Thyroid Studies Collaboration. Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis. J Clin Endocrinol Metab. 2015 Jun;100(6):2181-91. doi: 10.1210/jc.2015-1438. Epub 2015 Apr 9. Review. PMID: 25856213; PMCID: PMC4454799.
23. Lange-Maia BS, Strotmeyer ES, Harris TB, Glynn NW, Simonsick EM, Brach JS, Cauley JA, Richey PA, Schwartz AV, Newman AB; Health, Aging, and Body Composition Study. Physical Activity and Change in Long Distance Corridor Walk Performance in the Health, Aging, and Body Composition Study. J Am Geriatr Soc. 2015 Jul;63(7):1348-54. doi: 10.1111/jgs.13487. Epub 2015 Jun 11. PMID: 26096803; PMCID: PMC4770787.
24. Kline CE, Reboussin DM, Foster GD, Rice TB, Strotmeyer ES, Jakicic JM, Millman RP, Pi-Sunyer FX, Newman AB, Wadden TA, Zammit G, Kuna ST. The Effect of Changes in Cardiorespiratory Fitness and Weight on Obstructive Sleep Apnea Severity in Overweight Adults with Type 2 Diabetes. Sleep. 2016 Feb 1;39(2):317-25. doi: 10.5665/sleep.5436. PMID: 26446118; PMCID: PMC4712401.
25. Naples JG, Marcum ZA, Perera S, Gray SL, Newman AB, Simonsick EM, Yaffe K, Shorr RI, Hanlon JT; Health, Aging and Body Composition Study. Concordance Between Anticholinergic Burden Scales. J Am Geriatr Soc. 2015 Oct;63(10):2120-4. doi: 10.1111/jgs.13647. PMID: 26480974; PMCID: PMC4617193.
26. Bondoc I, Cochrane SK, Church TS, Dahinden P, Hettwer S, Hsu FC, Stafford RS, Pahor M, Buford TW; Life Study Investigators. Effects of a One-Year Physical Activity Program on Serum C-Terminal Agrin Fragment (CAF) Concentrations among Mobility-Limited Older Adults. J Nutr Health Aging. 2015 Nov;19(9):922-7. doi: 10.1007/s12603-015-0474-3. PMID: 26482694; PMCID: PMC4682669.
27. Santanasto AJ, Newman AB, Strotmeyer ES, Boudreau RM, Goodpaster BH, Glynn NW. Effects of Changes in Regional Body Composition on Physical Function in Older Adults: A Pilot Randomized Controlled Trial. J Nutr Health Aging. 2015;19(9):913-21. doi: 10.1007/s12603-015-0523-y. PMID: 26482693;
28. Schlenk EA, Bilt JV, Lo-Ciganic WH, Jacob ME, Woody SE, Conroy MB, Kwoh CK, Albert SM, Boudreau R, Newman AB, Zgibor JC. Pilot Enhancement of the Arthritis Foundation Exercise Program with a Healthy Aging Program. Res Gerontol Nurs. 2016 May 1;9(3):123-32. doi: 10.3928/19404921-20151019-04. Epub 2015 Oct 26. PMID: 26501346;
29. Kuller LH, Lopez OL, Becker JT, Chang Y, Newman AB. Risk of dementia and death in the long-term follow-up of the Pittsburgh Cardiovascular Health Study-Cognition Study. Alzheimers Dement. 2015 Oct 28. pii: S1552-5260(15)02907-6. doi: 10.1016/j.jalz.2015.08.165. [Epub ahead of print]. PMID: 26519786; PMCID: PMC4744537.
30. Singh J, Schupf N, Boudreau R, Matteini AM, Prasad T, Newman AB, Liu Y, Christensen K, Kammerer CM. Association of Aging-Related Endophenotypes With Mortality in 2 Cohort Studies: the Long Life Family Study and the Health, Aging and Body Composition Study. Am J Epidemiol. 2015 Dec 1;182(11):926-35. doi: 10.1093/aje/kwv143. Epub 2015 Nov 17. PMID: 26582777; PMCID: PMC4668756.
31. Flatt JD, Rosso AL, Aizenstein HJ, Schulz R, Longstreth WT Jr, Newman AB, Fowler NR, Rosano C. Social Network Size and Cranial Magnetic Resonance Imaging Findings in Older Adults: The Cardiovascular Health Study. J Am Geriatr Soc. 2015 Nov;63(11):2430-2. doi: 10.1111/jgs.13805. PMID: 26603076; PMCID: PMC4662082.
32. Thielke SM, Diehr PH, Yee LM, Arnold AM, Quiñones AR, Whitson HE, Jacob ME, Newman AB. Sex, Race, and Age Differences in Observed Years of Life, Healthy Life, and Able Life among Older Adults in The Cardiovascular Health Study. J Pers Med. 2015 Nov 25;5(4):440-51. doi: 10.3390/jpm5040440. PMID: 26610574; PMCID: PMC4695864.
33. Newman AB, Avilés-Santa ML, Anderson G, Heiss G, Howard WJ, Krucoff M, Kuller LH, Lewis CE, Robinson JG, Taylor H, Treviño RP, Weintraub W. Embedding Clinical Interventions into Observational Studies. Contemp Clin Trials. 2016 Jan;46:100-5. doi: 10.1016/j.cct.2015.11.017. Epub 2015 Dec 2. PMID: 26611435;
34. King AC, Salvo D, Banda JA, Ahn DK, Gill TM, Miller M, Newman AB, Fielding RA, Siordia C, Moore S, Folta S, Spring B, Manini T, Pahor M; LIFE Study Investigators. An observational study identifying obese subgroups among older adults at increased risk of mobility disability: do perceptions of the neighborhood environment matter? Int J Behav Nutr Phys Act. 2015 Dec 18;12(1):157. doi: 10.1186/s12966-015-0322-1. PMID: 26684894; PMCID: PMC4683911.
35. Garimella PS, Katz R, Patel KV, Kritchevsky SB, Parikh CR, Ix JH, Fried LF, Newman AB, Shlipak MG, Harris TB, Sarnak MJ; Health ABC Study. Association of Serum Erythropoietin With Cardiovascular Events, Kidney Function Decline, and Mortality: The Health Aging and Body Composition Study. Circ Heart Fail. 2016 Jan;9(1):e002124. doi: 10.1161/CIRCHEARTFAILURE.115.002124. PMID: 26721912; PMCID: PMC4698899.
36. Rosario BL, Rosso AL, Aizenstein HJ, Harris T, Newman AB, Satterfield S, Studenski SA, Yaffe K, Rosano C; Health ABC Study. Cerebral White Matter and Slow Gait: Contribution of Hyperintensities and Normal-appearing Parenchyma. J Gerontol A Biol Sci Med Sci. 2016 Jan 11. pii: glv224. [Epub ahead of print]. PMID: 26755683;
37. Raphael KL, Murphy RA, Shlipak MG, Satterfield S, Huston HK, Sebastian A, Sellmeyer DE, Patel KV, Newman AB, Sarnak MJ, Ix JH, Fried LF; Health ABC Study. Bicarbonate Concentration, Acid-Base Status, and Mortality in the Health, Aging, and Body Composition Study. Clin J Am Soc Nephrol. 2016 Feb 5;11(2):308-16. doi: 10.2215/CJN.06200615. Epub 2016 Jan 14. PMID: 26769766; PMCID: PMC4741040.
38. Fragala MS, Alley DE, Shardell MD, Harris TB, McLean RR, Kiel DP, Cawthon PM, Dam TT, Ferrucci L, Guralnik JM, Kritchevsky SB, Vassileva MT, Gudnason V, Eiriksdottir G, Koster A, Newman A, Siggeirsdottir K, Satterfield S, Studenski SA, Kenny AM. Comparison of Handgrip and Leg Extension Strength in Predicting Slow Gait Speed in Older Adults. J Am Geriatr Soc. 2016 Jan;64(1):144-50. doi: 10.1111/jgs.13871. PMID: 26782864;
39. Garg PK, Arnold AM, Hinckley Stukovsky KD, Koro C, Jenny NS, Mukamal KJ, Criqui MH, Furberg CD, Newman AB, Cushman M. Lipoprotein-Associated Phospholipase A2 and Incident Peripheral Arterial Disease in Older Adults: The Cardiovascular Health Study. Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):750-6. doi: 10.1161/ATVBAHA.115.306647. Epub 2016 Feb 4. PMID: 26848158; PMCID: PMC4808367.
40. Jacob ME, Lo-Ciganic WH, Simkin-Silverman LR, Albert SM, Newman AB, Terhorst L, Bilt JV, Zgibor JC, Schlenk EA. The preventive services use self-efficacy (PRESS) scale in older women: development and psychometric properties. BMC Health Serv Res. 2016 Feb 20;16(1):71. doi: 10.1186/s12913-016-1321-x. PMID: 26897364; PMCID: PMC4761175.
41. Beijers RJ, van den Borst B, Newman AB, Yende S, Kritchevsky SB, Cassano PA, Bauer DC, Harris TB, Schols AM; Health ABC Study. A Multidimensional Risk Score to Predict All-Cause Hospitalization in Community-Dwelling Older Individuals With Obstructive Lung Disease. J Am Med Dir Assoc. 2016 Jun 1;17(6):508-13. doi: 10.1016/j.jamda.2016.01.007. Epub 2016 Feb 23. PMID: 26926337; PMCID: PMC4884517.
42. Kuller LH, Lopez OL, Mackey RH, Rosano C, Edmundowicz D, Becker JT, Newman AB. Subclinical Cardiovascular Disease and Death, Dementia, and Coronary Heart Disease in Patients 80+ Years. J Am Coll Cardiol. 2016 Mar 8;67(9):1013-22. doi: 10.1016/j.jacc.2015.12.034. PMID: 26940919;
43. Lange-Maia BS, Cauley JA, Newman AB, Boudreau RM, Jakicic JM, Glynn NW, Zivkovic S, Dam T, Caserotti P, Cawthon PM, Orwoll ES, Strotmeyer ES. Sensorimotor Peripheral Nerve Function and Physical Activity in Older Men. J Aging Phys Act. 2016 Mar 11. [Epub ahead of print]. PMID: 26964668;
44. Callaghan BC, Xia R, Banerjee M, de Rekeneire N, Harris TB, Newman AB, Satterfield S, Schwartz AV, Vinik AI, Feldman EL, Strotmeyer ES; Health ABC study. Metabolic Syndrome Components Are Associated With Symptomatic Polyneuropathy Independent of Glycemic Status. Diabetes Care. 2016 Mar 10. pii: dc160081. [Epub ahead of print]. PMID: 26965720; PMCID: PMC4839175.
45. Dotson VM, Hsu FC, Langaee TY, McDonough CW, King AC, Cohen RA, Newman AB, Kritchevsky SB, Myers V, Manini TM, Pahor M. Genetic Moderators of the Impact of Physical Activity on Depressive Symptoms. J Frailty Aging. 2016;5(1):6-14. doi: 10.14283/jfa.2016.76. PMID: 26980363;
46. Henderson RM, Lovato L, Miller ME, Fielding RA, Church TS, Newman AB, Buford TW, Pahor M, McDermott MM, Stafford RS, Lee DS, Kritchevsky SB; LIFE Study Investigators. Effect of Statin Use on Mobility Disability and its Prevention in At-risk Older Adults: The LIFE Study. J Gerontol A Biol Sci Med Sci. 2016 Mar 17. pii: glw057. [Epub ahead of print]. PMID: 26988662;
47. Vaz Fragoso CA, Beavers DP, Anton SD, Liu CK, McDermott MM, Newman AB, Pahor M, Stafford RS, Gill TM; Lifestyle Interventions and Independence in Elders Investigators. Effect of Structured Physical Activity on Respiratory Outcomes in Sedentary Elderly Adults with Mobility Limitations. J Am Geriatr Soc. 2016 Mar;64(3):501-9. doi: 10.1111/jgs.14013. PMID: 27000324; PMCID: PMC4806401.
48. Zgibor JC, Schlenk EA, Vater L, Kola S, Bilt JV, Woody S, Jacob ME, Lo-Ciganic WH, Brenckle A, Brandenstein J, Kwoh CK, Boudreau R, Albert S, Conroy M, Rodgers E, Newman AB. Partnership Building and Implementation of an Integrated Healthy-Aging Program. Prog Community Health Partnersh. 2016;10(1):123-32. doi: 10.1353/cpr.2016.0001. PMID: 27018361;
49. Magnani JW, Wang N, Benjamin EJ, Garcia ME, Bauer DC, Butler J, Ellinor PT, Kritchevsky S, Marcus GM, Newman A, Phillips CL, Sasai H, Satterfield S, Sullivan LM, Harris TB; Health, Aging, and Body Composition Study. Atrial Fibrillation and Declining Physical Performance in Older Adults: The Health, Aging, and Body Composition Study. Circ Arrhythm Electrophysiol. 2016 May;9(5):e003525. doi: 10.1161/CIRCEP.115.003525. PMID: 27052031; PMCID: PMC4826757.
50. Druley TE, Wang L, Lin SJ, Lee JH, Zhang Q, Daw EW, Abel HJ, Chasnoff SE, Ramos EI, Levinson BT, Thyagarajan B, Newman AB, Christensen K, Mayeux R, Province MA. Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study. BMC Geriatr. 2016 Apr 9;16(1):80. doi: 10.1186/s12877-016-0253-y. PMID: 27060904; PMCID: PMC4826550.
51. Best JR, Liu-Ambrose T, Boudreau RM, Ayonayon HN, Satterfield S, Simonsick EM, Studenski S, Yaffe K, Newman AB, Rosano C; Health, Aging and Body Composition Study. An Evaluation of the Longitudinal, Bidirectional Associations Between Gait Speed and Cognition in Older Women and Men. J Gerontol A Biol Sci Med Sci. 2016 Apr 10. pii: glw066. [Epub ahead of print]. PMID: 27069098;
52. Willcox BJ, Tranah GJ, Chen R, Morris BJ, Masaki KH, He Q, Willcox DC, Allsopp RC, Moisyadi S, Poon LW, Rodriguez B, Newman AB, Harris TB, Cummings SR, Liu Y, Parimi N, Evans DS, Davy P, Gerschenson M, Donlon TA. The FoxO3 gene and cause-specific mortality. Aging Cell. 2016 Apr 13. doi: 10.1111/acel.12452. [Epub ahead of print]. PMID: 27071935;
53. Barbour KE, Lui LY, McCulloch CE, Ensrud KE, Cawthon PM, Yaffe K, Barnes DE, Fredman L, Newman AB, Cummings SR, Cauley JA; Study of Osteoporotic Fractures. Trajectories of Lower Extremity Physical Performance: Effects on Fractures and Mortality in Older Women. J Gerontol A Biol Sci Med Sci. 2016 Apr 15. pii: glw071. [Epub ahead of print]. PMID: 27084313;
54. Santanasto AJ, Coen PM, Glynn NW, Conley KE, Jubrias SA, Amati F, Strotmeyer ES, Boudreau RM, Goodpaster BH, Newman AB. The relationship between mitochondrial function and walking performance in older adults with a wide range of physical function. Exp Gerontol. 2016 Apr 12;81:1-7. doi: 10.1016/j.exger.2016.04.002. [Epub ahead of print]. PMID: 27084585;
55. McCabe EL, Larson MG, Lunetta KL, Newman AB, Cheng S, Murabito JM. Association of an Index of Healthy Aging With Incident Cardiovascular Disease and Mortality in a Community-Based Sample of Older Adults. J Gerontol A Biol Sci Med Sci. 2016 Apr 26. pii: glw077. [Epub ahead of print]. PMID: 27117172;
56. Odden MC, Wu C, Shlipak MG, Psaty BM, Katz R, Applegate WB, Harris T, Newman AB, Peralta CA; Health ABC Study. Blood Pressure Trajectory, Gait Speed, and Outcomes: The Health, Aging, and Body Composition Study. J Gerontol A Biol Sci Med Sci. 2016 May 3. pii: glw076. [Epub ahead of print]. PMID: 27142696;
57. Murphy RA, Bureyko TF, Miljkovic I, Cauley JA, Satterfield S, Hue TF, Klepin HD, Cummings SR, Newman AB, Harris TB. Association of total adiposity and computed tomographic measures of regional adiposity with incident cancer risk: a prospective population-based study of older adults. Appl Physiol Nutr Metab. 2014 Jun;39(6):687-92. doi: 10.1139/apnm-2013-0360. Epub 2013 Dec 4. PMID: 24869972; PMCID: PMC4071344.
58. Nadkarni NK, Perera S, Hanlon JT, Lopez O, Newman AB, Aizenstein H, Elam M, Harris TB, Kritchevsky S, Yaffe K, Rosano C. Statins and brain integrity in older adults: secondary analysis of the Health ABC study. Alzheimers Dement. 2015 Oct;11(10):1202-11. doi: 10.1016/j.jalz.2014.11.003. Epub 2015 Jan 12. PMID: 25592659; PMCID: PMC4499493.
59. Espeland MA, Newman AB, Sink K, Gill TM, King AC, Miller ME, Guralnik J, Katula J, Church T, Manini T, Reid KF, McDermott MM; LIFE Study Group. Associations Between Ankle-Brachial Index and Cognitive Function: Results From the Lifestyle Interventions and Independence for Elders Trial. J Am Med Dir Assoc. 2015 Aug 1;16(8):682-9. doi: 10.1016/j.jamda.2015.03.010. Epub 2015 Apr 11. PMID: 25869993; PMCID: PMC4516564.
60. Murphy RA, Hagaman AK, Reinders I, Steeves JA, Newman AB, Rubin SM, Satterfield S, Kritchevsky SB, Yaffe K, Ayonayon HN, Nagin DS, Simonsick EM, Penninx BW, Harris TB; Health ABC Study. Depressive Trajectories and Risk of Disability and Mortality in Older Adults: Longitudinal Findings From the Health, Aging, and Body Composition Study. J Gerontol A Biol Sci Med Sci. 2016 Feb;71(2):228-35. doi: 10.1093/gerona/glv139. Epub 2015 Aug 13. PMID: 26273025; PMCID: PMC4723662.
61. Brown PJ, Roose SP, Zhang J, Wall M, Rutherford BR, Ayonayon HN, Butters MA, Harris T, Newman AB, Satterfield S, Simonsick EM, Yaffe K. Inflammation, Depression, and Slow Gait: A High Mortality Phenotype in Later Life. J Gerontol A Biol Sci Med Sci. 2016 Feb;71(2):221-7. doi: 10.1093/gerona/glv156. Epub 2015 Sep 20. PMID: 26392405; PMCID: PMC4723663.
62. Naples JG, Marcum ZA, Perera S, Newman AB, Greenspan SL, Gray SL, Bauer DC, Simonsick EM, Shorr RI, Hanlon JT. Impact of Drug-Drug and Drug-Disease Interactions on Gait Speed in Community-Dwelling Older Adults. Drugs Aging. 2016 Jun;33(6):411-8. doi: 10.1007/s40266-016-0373-2. PMID: 27138955; PMCID: PMC4873384.
63. Marsh AP, Applegate WB, Guralnik JM, Jack Rejeski W, Church TS, Fielding RA, Gill TM, King AC, Kritchevsky SB, Manini TM, McDermott MM, Newman AB, Stowe CL, Walkup MP, Pahor M, Miller ME; LIFE Study Investigators. Hospitalizations During a Physical Activity Intervention in Older Adults at Risk of Mobility Disability: Analyses from the Lifestyle Interventions and Independence for Elders Randomized Clinical Trial. J Am Geriatr Soc. 2016 May;64(5):933-43. doi: 10.1111/jgs.14114. PMID: 27225353; PMCID: PMC4887151.
64. Newman AB, Sanders JL, Kizer JR, Boudreau RM, Odden MC, Zeki Al Hazzouri A, Arnold AM. Trajectories of function and biomarkers with age: the CHS All Stars Study. Int J Epidemiol. 2016 Jun 6. pii: dyw092. [Epub ahead of print]; doi: 10.1093/ije/dyw092. PMID: 27272182.
65. Albert SM, Lunney JR, Ye L, Boudreau R, Ives D, Satterfield S, Ayonayon HN, Rubin SM, Newman AB, Harris T; Health ABC Study. Symptom Burden and End-of-Life Treatment Preferences in the Very Old. J Pain Symptom Manage. 2016 Jun 2. pii: S0885-3924(16)30142-7. doi: 10.1016/j.jpainsymman.2016.03.009. [Epub ahead of print] PubMed PMID: 27265815.
66. Sanders JL, Singh J, Minster RL, Walston JD, Matteini AM, Christensen K, Mayeux R, Borecki IB, Perls T, Newman AB; Long Life Family Study Research Group. Association Between Mortality and Heritability of the Scale of Aging Vigor in Epidemiology. J Am Geriatr Soc. 2016 Jun 13. doi: 10.1111/jgs.14190. [Epub ahead of print] PubMed PMID: 27294813.
67. Sanders JL, Arnold AM, Hirsch CH, Thielke SM, Kim D, Mukamal KJ, Kizer JR, Ix JH, Kaplan RC, Kritchevsky SB, Newman AB. Effects of Disease Burden and Functional Adaptation on Morbidity and Mortality on Older Adults. J Am Geriatr Soc. 2016 Jun;64(6):1242-9. doi: 10.1111/jgs.14163. PubMed PMID: 27321602.
68. Newman AB, Dodson JA, Church TS, Buford TW, Fielding RA, Kritchevsky S, Beavers D, Pahor M, Stafford RS, Szady AD, Ambrosius WT, McDermott MM; LIFE Study Group. Cardiovascular Events in a Physical Activity Intervention Compared With a Successful Aging Intervention: The LIFE Study Randomized Trial. JAMA Cardiol. 2016 Jun 29. doi: 10.1001/jamacardio.2016.1324. [Epub ahead of print] PubMed PMID: 27439082.
69. Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M, Broer L; CHARGE Longevity Working Group, Cappola A, Ceda GP, Chanock S, Chen MH, Chen TC, Chen YI, Chung J, Del Greco Miglianico F, Eriksson J, Ferrucci L, Friedrich N, Gnewuch C, Goodarzi MO, Grarup N, Guo T, Hammer E, Hayes RB, Hicks AA, Hofman A, Houwing-Duistermaat JJ, Hu F, Hunter DJ, Husemoen LL, Isaacs A, Jacobs KB, Janssen JA, Jansson JO, Jehmlich N, Johnson S, Juul A, Karlsson M, Kilpelainen TO, Kovacs P, Kraft P, Li C, Linneberg A, Liu Y, Loos RJ; Body Composition Genetics Consortium, Lorentzon M, Lu Y, Maggio M, Magi R, Meigs J, Mellström D, Nauck M, Newman AB, Pollak MN, Pramstaller PP, Prokopenko I, Psaty BM, Reincke M, Rimm EB, Rotter JI, Saint Pierre A, Schurmann C, Seshadri S, Sjögren K, Slagboom PE, Strickler HD, Stumvoll M, Suh Y, Sun Q, Zhang C, Svensson J, Tanaka T, Tare A, Tönjes A, Uh HW, van Duijn CM, van Heemst D, Vandenput L, Vasan RS, Völker U, Willems SM, Ohlsson C, Wallaschofski H, Kaplan RC. Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. 2016 Jun 21. doi: 10.1111/acel.12490. [Epub ahead of print] PubMed PMID: 27329260.
70. Matteini AM, Tanaka T, Karasik D, Atzmon G, Chou WC, Eicher JD, Johnson AD, Arnold AM, Callisaya ML, Davies G, Evans DS, Holtfreter B, Lohman K, Lunetta KL, Mangino M, Smith AV, Smith JA, Teumer A, Yu L, Arking DE, Buchman AS, Chibinik LB, De Jager PL, Evans DA, Faul JD, Garcia ME, Gillham-Nasenya I, Gudnason V, Hofman A, Hsu YH, Ittermann T, Lahousse L, Liewald DC, Liu Y, Lopez L, Rivadeneira F, Rotter JI, Siggeirsdottir K, Starr JM, Thomson R, Tranah GJ, Uitterlinden AG, Völker U, Völzke H, Weir DR, Yaffe K, Zhao W, Zhuang WV, Zmuda JM, Bennett DA, Cummings SR, Deary IJ, Ferrucci L, Harris TB, Kardia SL, Kocher T, Kritchevsky SB, Psaty BM, Seshadri S, Spector TD, Srikanth VK, Windham BG, Zillikens MC, Newman AB, Walston JD, Kiel DP, Murabito JM. GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium. Aging Cell. 2016 Jun 21. doi: 10.1111/acel.12468. [Epub ahead of print] PubMed PMID: 27325353.