Dr. Adam Santanasto, PhD, MPH

Assistant Professor, Epidemiology


R-znvy: nwf06@cvgg.rqh
Primary Phone: 967-838-6850

Personal Statement

Research interests:
-Skeletal muscle aging

-Molecular epidemiology of skeletal muscle aging, physical
function and mobility

-Body composition remodeling and its effects on physical function
and mobility

-Prevention of mobility disability and prolonging years of active
life expectancy


2008 | University of Pittsburgh, Pittsburgh, PA, USA | BS, Health Information Management

2010 | University of Pittsburgh, Pittsburgh, PA, USA | MPH, Epidemiology

2013| University of Pittsburgh, Pittsburgh, PA, USA | PhD, Epidemiology

Selected Publications

1. Baker JF, Long J, Leonard MB, Harris T, Delmonico MJ, Santanasto A, Satterfield S, Zemel B, Weber DR. Estimation of Skeletal Muscle Mass Relative to Adiposity Improves Prediction of Physical Performance and Incident Disability. J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):946-952. PubMed PMID: 28958026; PubMed Central PMCID: PMC6001879.

2. Cooper R, Popham M, Santanasto AJ, Hardy R, Glynn NW, Kuh D. Are BMI and inflammatory markers independently associated with physical fatigability in old age? Int J Obes (Lond). 2018 May 24;PubMed PMID: 29795469.

3. Pérez LM, Roqué M, Glynn NW, Santanasto AJ, Ramoneda M, Molins MT, Coll-Planas L, Vidal P, Inzitari M. Validation of the Spanish version of the Pittsburgh Fatigability Scale for older adults. Aging Clin Exp Res. 2018 May 8;PubMed PMID: 29736892.

4. Miller ME, Magaziner J, Marsh AP, Fielding RA, Gill TM, King AC, Kritchevsky S, Manini T, McDermott MM, Neiberg R, Orwig D, Santanasto AJ, Pahor M, Guralnik J, Rejeski WJ. Gait Speed and Mobility Disability: Revisiting Meaningful Levels in Diverse Clinical Populations. J Am Geriatr Soc. 2018 May;66(5):954-961. PubMed PMID: 29608795; NIHMSID: NIHMS948318; PubMed Central PMCID: PMC5992037.

5. Santanasto AJ, Miljkovic I, Cvejkus RC, Gordon CL, Bunker CH, Patrick AL, Wheeler VW, Zmuda JM. Body Composition Remodeling and Incident Mobility Limitations in African Ancestry Men. J Gerontol A Biol Sci Med Sci. 2018 Apr 5;PubMed PMID: 29659706.

6. Chen H, Ambrosius WT, Murphy TE, Fielding R, Pahor M, Santanasto A, Tudor-Locke C, Jack Rejeski W, Miller ME. Imputation of Gait Speed for Noncompleters in the 400-Meter Walk: Application to the Lifestyle Interventions for Elders Study. J Am Geriatr Soc. 2017 Dec;65(12):2566-2571. PubMed PMID: 28884789; NIHMSID: NIHMS898649; PubMed Central PMCID: PMC5729108.

7. Forman DE, Santanasto AJ, Boudreau R, Harris T, Kanaya AM, Satterfield S, Simonsick EM, Butler J, Kizer JR, Newman AB. Impact of Incident Heart Failure on Body Composition Over Time in the Health, Aging, and Body Composition Study Population. Circ Heart Fail. 2017 Sep;10(9)PubMed PMID: 28899988; NIHMSID: NIHMS900696; PubMed Central PMCID: PMC5658007.

8. Santanasto AJ, Glynn NW, Lovato LC, Blair SN, Fielding RA Gill TM, Guralnik JM, Hsu FC, King AC, Strotmeyer ES, Manini TM, Marsh AP, McDermott MM, Goodpaster BH, Pahor M, Newman AB. Effect of Physical Activity versus Health Education on Physical Function, Grip Strength and Mobility. J Am Geriatr Soc. 2017 Jul;65(7):1427-1433. PubMed PMID: 28221668; NIHMSID: NIHMS837860; PubMed Central PMCID: PMC5507738.

9. Shepherd JA, Ng BK, Fan B, Schwartz AV, Cawthon P, Cummings SR, Kritchevsky S, Nevitt M, Santanasto A, Cootes TF. Modeling the shape and composition of the human body using dual energy X-ray absorptiometry images. PLoS One. 2017;12(4):e0175857. PubMed PMID: 28423041; PubMed Central PMCID: PMC5397033.

10. Santanasto AJ, Goodpaster BH, Kritchevsky SB, Miljkovic I, Satterfield S, Schwartz AV, Cummings SR, Boudreau RM, Harris TB, Newman AB. Body Composition Remodeling and Mortality: The Health Aging and Body Composition Study. J Gerontol A Biol Sci Med Sci. 2017 Apr 1;72(4):513-519. PubMed PMID: 27567109; PubMed Central PMCID: PMC5897837.

11. Ó Hartaigh B, Lovato LC, Pahor M, Buford TW, Dodson JA, Forman DE, Buman MP, Demons JL, Santanasto AJ, Liu C, Miller ME, McDermott MM, Gill TM. Effect of a Long-Term Physical Activity Intervention on Resting Pulse Rate in Older Persons: Results from the Lifestyle Interventions and Independence for Elders Study. J Am Geriatr Soc. 2016 Dec;64(12):2511-2516. PubMed PMID: 27787876; NIHMSID: NIHMS786819; PubMed Central PMCID: PMC5173403.

12. Santanasto AJ, Coen PM, Glynn NW, Conley KE, Jubrias SA, Amati F, Strotmeyer ES, Boudreau RM, Goodpaster BH, Newman AB.. The relationship between mitochondrial function and walking performance in older adults with a wide range of physical function. Exp Gerontol. 2016 Aug;81:1-7. PubMed PMID: 27084585; NIHMSID: NIHMS862125; PubMed Central PMCID: PMC5483943.

13. Santanasto AJ, Glynn NW, Jubrias SA, Conley KE, Boudreau RM, Amati F, Mackey DC, Simonsick EM, Strotmeyer ES, Coen PM, Goodpaster BH, Newman AB. Skeletal Muscle Mitochondrial Function and Fatigability in Older Adults. J Gerontol A Biol Sci Med Sci. 2015 Nov;70(11):1379-85. PubMed PMID: 25167867; PubMed Central PMCID: PMC4612379.

14. Santanasto AJ, Newman AB, Strotmeyer ES, Boudreau RM, Goodpaster BH, Glynn NW. Effects of Changes in Regional Body Composition on Physical Function in Older Adults: A Pilot Randomized Controlled Trial. J Nutr Health Aging. 2015 Nov;19(9):913-21. PubMed PMID: 26482693.

15. Glynn NW, Santanasto AJ, Simonsick EM, Boudreau RM, Beach SR, Schulz R, Newman AB. The Pittsburgh Fatigability scale for older adults: development and validation. J Am Geriatr Soc. 2015 Jan;63(1):130-5. PubMed PMID: 25556993; NIHMSID: NIHMS800130; PubMed Central PMCID: PMC4971882.

16. Santanasto AJ, Glynn NW, Newman MA, Taylor CA, Brooks MM, Goodpaster BH, Newman AB. Impact of weight loss on physical function with changes in strength, muscle mass, and muscle fat infiltration in overweight to moderately obese older adults: a randomized clinical trial. J Obes. 2011;2011PubMed PMID: 20953373; PubMed Central PMCID: PMC2952914.

Adam  Santanasto