Directory Calendar News Careers Alumni Giving

Biostatistics Seminars

Department of Biostatistics Seminar Series


The Department of Biostatistics presents a regular speaker series each semester, generally on Thursday afternoon each week. Diverse experts lecture on their work in biostatistics.

Upcoming Biostats Seminars

Biostatistics Seminar Series

Dynamic functional clustering with applications to the MAPP Study-Wensheng Guo-UPenn

Thursday 4/19 3:30PM - 4:30PM
Public Health Lecture Hall (A115)

Biostatistics guest speaker, Wensheng Guo, University of Pennsylvania, will present, "Dynamic functional clustering with applications to Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) study."

In this talk, I will present some works under development by our group on functional clustering and dimension reduction methods. The proposed methods are motivated by, and are applied to the data collected in the NIDDK-funded Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. This is a longitudinal cohort study that collects high dimensional longitudinal urological chronic pelvic pain syndrome (UCPPS) symptom data together with many other biomarkers, neuroimaging data and genetic data. The goal of the study is to identify risk factors that can predict whether a subject would be worsening or improving and to understand the underlying pathological mechanisms. We first propose a dynamic functional clustering algorithm where each group of curves are modeled by a functional mixed effects model, and the posterior probability is used to iteratively classify each subject into different subgroups.  The functional mixed effects model allows flexible designs and nested structures. The classification takes into account both group-average trajectories and between-subject variability. We propose an equivalent dynamic state space model to calculate the likelihood in fitting the model, and to efficiently compute the posterior probability in classifying a new subject. The resultant sequential algorithm is O(n) and can be implemented online. We also propose a leave-one-subject-out cross-validation Kullback-Leibler information criterion to choose the number of clusters.  The performance is assessed through a simulation study, and we apply the proposed methods to longitudinal urological chronic pelvic pain syndrome symptom data collected in the MAPP Research  Network and identify three subgroups 

Last Updated On Wednesday, March 28, 2018 by Temp, GSPH Marketing & Development
Created On Friday, January 05, 2018

Previous Biostats Seminars

Thu 12/6/2018
Biostatistics Faculty Presentations: Jeanine M. Buchanich and Yongseok Park Biostatistics Seminar Series
Biostatistics Faculty Presentations: Jeanine M. Buchanich and Yongseok Park
Thu 12/6/2018 3:30PM - 4:30PM
Public Health Auditorium (G23)

Thu 11/29/2018
Dulal K. Bhaumik, University of Illinois at Chicago Biostatistics Seminar Series
Dulal K. Bhaumik, University of Illinois at Chicago
Thu 11/29/2018 3:30PM - 4:30PM
Public Health Auditorium (G23)

Dulal K. Bhaumik, Division of Epidemiology and Biostatistics, University of Illinois at Chicago, will present, “Statistical Methodologies for Neuroconnectivity Analysis Using Autistic fMRI Data”.
Thu 11/8/2018
Hongzhe Lee, University of Pennsylvania Biostatistics Seminar Series
Hongzhe Lee, University of Pennsylvania
Thu 11/8/2018 3:30PM - 4:30PM
Public Health Auditorium (G23)

Hongzhe Lee, Department of Biostatistics and Epidemiology, University of Pennsylvania, will present, “Optimal Permutation Recovery and Estimation of Bacterial Growth Dynamics”.
Thu 11/1/2018
Jingyi (Jessica) Li, University of California, Los Angeles Biostatistics Seminar Series
Jingyi (Jessica) Li, University of California, Los Angeles
Thu 11/1/2018 3:30PM - 4:30PM
Public Health Auditorium (G23)

Jingyi (Jessica) Li, Department of Statistics and Department of Human Genetics, University of California, Los Angeles, will present, “Neyman-Pearson Classification Algorithms and NP Receiver Operating Characteristics”.
Thu 10/25/2018
Dana L. Tudorascu, University of Pittsburgh Biostatistics Seminar Series
Dana L. Tudorascu, University of Pittsburgh
Thu 10/25/2018 3:30PM - 4:30PM
Public Health Auditorium (G23)

Dana Tudorascu, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, will present, “Technical Challenges in the Statistical Analysis of Neuroimaging Studies of Alzheimer's Disease”.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

Contact

For information on seminars and events in the department, contact:

Bernadette Kapko
bkapko@pitt.edu
412-624-3022

© 2018 by University of Pittsburgh Graduate School of Public Health

Login  |  Sitemap