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Rappocciolo presents research on cell cholesterol dysregulation in HIV non-progressors at 2018 Conference on Retroviruses and Opportunistic Infections

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IDM's GIOVANNA RAPPOCCIOLO presented at the Conference on Retroviruses and Opportunistic Infections ion biomarkers and genetics of cell cholesterol dysregulation in HIV non-progressors. Co-authors include IDM faculty J MARTINSON and C RINALDO and recent doctoral graduate DIANA DELUCIA.   

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques

JOURNAL OF IMMUNOLOGY - Wonderlich, Swan, Bissel, Hartman, Carney, O'Malley, Obadan, Santos, Walker, Sturgeon, Frye, Maiello, Scanga, Bowling, Duangkhae, Wiley, Flynn, Wang, Cole, Reed, Barratt-Boyes establish a new nonhuman primate disease model for evaluation of vaccine and therapeutic approaches to prevent and treat infection with highly pathogenic avian influenza viruses.   

Amid opioid crisis, Frank addresses Titusville community

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TITUSVILLE HERALD - Community members and students from Pitt's Titusville campus gathered to hear IDM's LINDA FRANK discuss drug misuse versus drug abuse, the opioid epidemic's relation to to the spread of HIV/AIDS and Hepatitis C, available prevention and treatment strategies, and the implications for health professionals, families, community members, and local organizations.   

As Zika babies become toddlers, some can’t see, walk, or talk

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NEW YORK TIMES - Infectious disease researcher ERNESTO MARQUES says about 3 percent of 1,000 pregnant Brazilian women in a recent sample were infected with Zika. “The problem’s not going away. We are still having cases. And the future of Zika babies already born is complicated by poverty and strained resources. “Most of these babies are from low socioeconomic status and rely on the public health system to provide care. It’s very difficult to mana... 

Mailliard presents research on improving HIV “kick and kill” strategies to IAS Conference on HIV Science in Paris (Video)

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YOUTUBE - IDM's Mailliard presents his research on “kick and kill” strategies at the 9th IAS Conference on HIV Science, the world's largest open scientific conference on HIV and AIDS-related issues. The work demonstrates that naïve T cells have the ability to effectively target the HIV-1 reservoir, highlighting the importance of directing HIV-1 curative strategies towards the induction of de novo rather than memory HIV-1-specific CTL responses.  

Stall's research helps to "Kick ASS"

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SAN FRANCISCO BAY TIMES - The reality of AIDS Survivor Syndrome (ASS) is now being confirmed by empirical research. On November 3, 2017, BCHS Associate Chair for Science RON STALL presented his findings on the subject in San Francisco at a provider and community town hall entitled “Research on the AIDS Survivor Syndrome: New Data from The Multi-Center AIDS Cohort Study and Voices of Survivors Themselves.” 

Marques: While Zika hasn’t been in the news much, that doesn’t mean it’s gone

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WASHINGTON POST - Local transmission seems to have come to a standstill, with one suspected case in Texas and one case confirmed in Florida. Herd immunity may be preventing more big outbreaks. But if Zika behaves like other arboviruses, it will probably stick around. They tend to be cyclical, says Pitt Public Health researcher ERNESTO MARQUES. “You have big booms, then they drop. Then a few years later, they come back again.” 

Enigma: Marques worked to pinpoint culprit of mysterious illness in Brazil

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PITTWIRE - When a mysterious illness suddenly emerged in his Brazilian hometown, IDM researcher ERNESTO MARQUES mobilized with colleagues to decode its unknowns. The work may help infectious-disease researchers stop or stall new epidemics. His story begins on page 18. 

Frank on Telehealth Appalachian AIDS Education and Training (video)

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The Telehealth Appalachian AIDS Education and Training Center Project, led by IDM's LINDA FRANK, provides web-based HIV education, training, clinical guidelines, and resources to Appalachian community health centers. Frank has worked to increase knowledge and awareness about HIV disease in underserved communities in the hope of preventing discrimination and delivering more care to those who need it.  

Marques: Zika virus still offers no clear answers

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THE GLOBE AND MAIL - It has been two years since Brazil’s northeast was hit with the public-health crisis that left babies born with CZS and set off alarm bells in the global health community. Yet experts continue to grapple with big questions. “We can’t really tell if what happened here was replicated or not in other areas of Brazil or Latin America because we don’t really know how many women were exposed,” said IDM’s ERNESTO MARQUES, who is con... 

Frank addresses surgeon general report on opioid epidemic (video)

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WPXI - "We've got to increase public health awareness of addiction. A lot of people think, 'It's not my family, it's not me, it's not my community,' and we know that it can be anybody." IDM's LINDA FRANK talks to NIGHTTalk about opioid addiction in Pittsburgh and around the country.  

2017 faculty and staff Delta Omega initiates

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The following four individuals will be inducted into the Omicron chapter of the Delta Omega Honorary Society at the Graduate School of Public Health, recognizing merit and encouraging further excellence in, and devotion to, public health work: Nancy W. Glynn (EPI '94), faculty and alumna; Leah M. Lamonte (IDM '06), alumna; Natalie A. Solomon-Brimage (BCHS '06), alumna; Christopher A. Taylor (EPI '10), alumnus. 

Rotarian director talks with Salk and Burke about polio eradication (video)

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A round-table was held today with some amazing minds on the issue of polio eradication: Jennifer Jones, director of Rotary International; PETER SALK, IDM visiting professor and son of research pioneer Jonas Salk; and DONALD BURKE, school dean and University associate vice chancellor of global health. Rotary has been raising awareness that "We are this close to ending polio!" While all were in Pittsburgh, they shared amazing conversation about the... 

IDM's Peter Salk on importance of Julius Youngner, polio vaccine pioneer, dead at 96

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NEW YORK TIMES - “I think it’s absolutely fair to say that had it not been for Dr. Youngner, the polio vaccine would not have come into existence,” PETER SALK president of the Jonas Salk Legacy Foundation and a visiting professor at the University of Pittsburgh Graduate School of Public Health, said in an e-mail. He added, “The really important thing to recognize is that the development of the polio vaccine at the University of Pittsburgh was a t... 

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Recent IDM Publications

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques 

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques

JOURNAL OF IMMUNOLOGY - Wonderlich, Swan, Bissel, Hartman, Carney, O'Malley, Obadan, Santos, Walker, Sturgeon, Frye, Maiello, Scanga, Bowling, Duangkhae, Wiley, Flynn, Wang, Cole, Reed, Barratt-Boyes establish a new nonhuman primate disease model for evaluation of vaccine and therapeutic approaches... (02/14/2018)

Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4+ T cells 

Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4+ T cells

NATURE MEDICINE - Gupta, Sanyal, Ratner, Ding, Zerbato, Giacobbi, Venkatachari, Patterson, Chargin, Chen, Mailliard, Rinaldo, and Sluis-Cremer found that the size of the inducible latent HIV-1 reservoir in aviremic subjects on ART is approximately 70-fold larger than previous estimates.  (02/08/2018)

Peripheral blood biomarkers of disease outcome in a monkey model of rift valley fever encephalitis.  

Peripheral blood biomarkers of disease outcome in a monkey model of rift valley fever encephalitis.

JOURNAL OF VIROLOGY - Wonderlich, Caroline, McMillen, Walters, Reed, Barratt-Boyes, and Hartman conclude that African green monkeys are a novel and suitable model for studying the neuropathogenesis of Rift Valley Fever (RVF) and for testing vaccines and therapeutics against this important emerging ... (02/05/2018)
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