IDM Department News

Frank on PrEP: A drug proven to prevent HIV is still slow to catch on

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TRIB LIVE - Physicians also need to be included in education around prescribing and using PrEP, said IDM's Linda Frank. That goes beyond making sure their patients take a pill a day. It includes working with communities to make sure people have the support and counseling to make healthy decisions. She said, “It’s important to have treatments and vaccines, but we still have to work on that other side of the equation: How do you get people to chan... 

Koenig presents at Midwest Virology Meeting

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Zachary Koenig (IDM '20) was selected for an oral presentation at the Midwest Virology Symposium held at Ohio State University October 11-13. The title of his talk was "Type III Interferon Control of Rift Valley Fever Virus Infection at Epithelial Cell Barriers." Koenig also won a student travel award to attend the conference.   

Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States

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AIDS AND BEHAVIOR - Friedman, MR, Sang, JM, Bukowski, LA, Chandler, CJ, Egan, JE, Eaton, LA, Matthews, DD, Ho, K, Raymond, HF, & Stall, R. found that PrEP awareness campaigns tailored for black men who have sex with men and women (MSMW), concomitant with STI-to-PrEP interventions, will facilitate greater PrEP uptake in this population.  

IDM Research Day expanded with guest speakers and more than 70 student presenters

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The Department of Infectious Diseases and Microbiology held their biggest-ever research day celebration, featuring three guest speakers: Jonathan Oliver spoke about the emerging tick-borne diseases of the northern United States, Daniel Voth talked about using human-derived systems to investigate bacterial pulmonary infection, and David Lampe lectured on inhibiting the spread of malaria by altering the mosquito microbiome.    

Henning breaks down the risks associated with ticks

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THE TRIBUNE-DEMOCRAT - In the past century, Pennsylvania has become very favorable for the ecology of tick-borne diseases. The region's woodlands, rivers, growing white tailed-deer population, plentiful population of white-footed mouse, and the expansion of human populations into the black-legged tick's habitat create ideal conditions for the transmission of Lyme disease to humans. Jill Henning (IDM '08) breaks down the risks.    

Smith talks in-depth immunotherapy for lung cancer

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HOPE WITH ANSWERS - Discover in-depth information about immunotherapy for lung cancer through this conversation between Kellie Smith (IDM '13) of Johns Hopkins and patient advocate Lysa Buonanno, part of a video series providing the next level of information for patients to understand treatment options, particularly if they've experienced resistances or if their lung cancer has progressed.   

MidAtlantic AIDS Education & Training Center receives $14.2 million to extend efforts into 2024

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INSIDE UPMC - Public health alumnae & RPCVs Marilyn Blasingame (IDM '16) and Ingrid Godfrey (IDM '18), and IDM professor Linda Rose Frank discuss their work on the prevention and treatment  of HIV/AIDS and its co-morbidities through the MidAtlantic AIDS Education & Training Center (MAAETC), which recently was awarded $14.2 million from the Department of Health and Human Services to continue the center’s work for the next five years  

Zika and travel: Marques tells you what you need to know

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THE NEW YORK TIMES - The virus has been out of the headlines, but that doesn't mean it is gone. The World Health Organization just updated guideines for travelling to the Zika zone. "Summer in the north is winter in the south and vice versa, so you have to consider that," said IDM's Ernesto Marques. The virus is still circulating, but it's less prevalent in colder months than in the summer.   

The Zika virus is still a threat. Here's what Marques, other experts know

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THE NEW YORK TIMES - Remember Zika? With measles and Ebola grabbing headlines, it is easy to forget the health panic of 2016, when Zika was linked to severe birth defects in thousands of Brazilian newborns whose mothers were infected while pregnant, striking fear across the country and much of the Americas. "The next outbreak is not a matter of if, but when," said IDM's Ernesto Marques.   

Pitt Men's Study reflects on past, future of HIV fight

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THE PITT NEWS - When an outbreak of HIV hit the U.S. in the early 1980s, not much was known about the virus or how it spread. Scientists, researchers, and volunteers at Pitt have been working for almost four decades to try and change that. Reflecting on 40 years means celebrating successes, lamenting that the cure hasn't yet been found, and commending those original study participants that came forward in a tumultuous and uncertain time.   

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Recent IDM Publications

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Rubio publishes thesis in Antimicrobial Agents and Therapy 

Rubio publishes thesis in Antimicrobial Agents and Therapy

Abigail Rubio (IDM '20) recently published In vitro Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa following Treatment-emergent Resistance to Ceftolozane-tazobactam, comparing the in vitro susceptibility of multidrug-resistant Pseudomonas aeruginosa isolates 34 collected before and af... (04/20/2021)

Zika-related adverse outcomes in a cohort of pregnant women with rash in Pernambuco, Brazil 

Zika-related adverse outcomes in a cohort of pregnant women with rash in Pernambuco, Brazil

Multiple authors on behalf of the Microcephaly Epidemic Research Group, including IDM's Ernesto Marques, found the frequency of microcephaly in their results is consistent with previous studies. In addition, as children were evaluated at a later age and repeatedly by different groups of specialists... (03/19/2021)

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts 

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts

Amy L. Hartman, Sham Nambulli, Cynthia M. McMillen, Alexander G. White, Natasha Louise Tilston-Lunel, Joseph R. Albe, Emily Cottle, Matthew D. Dunn, L. James Frye, Theron H. Gilliland, Emily L. Olsen, Katherine J. O’Malley, Madeline M. Schwarz, Jaime A. Tomko, Reagan C. Walker, Mengying Xia, Matthe... (11/17/2020)

Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function 

Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function

Colleen R. Zaccard, Lauren Shapiro, Maria D. Martin-de-Saavedra, Christopher Pratt, Kristoffer Myczek, Amy Song, Marc P. Forrest, Peter Penzes Dendritic spinules are thin protrusions, formed by neuronal spines, not adequately resolved by diffraction-limited light microscopy, which has limit... (11/17/2020)
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Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States 

Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States

AIDS AND BEHAVIOR - Friedman, MR, Sang, JM, Bukowski, LA, Chandler, CJ, Egan, JE, Eaton, LA, Matthews, DD, Ho, K, Raymond, HF, & Stall, R. found that PrEP awareness campaigns tailored for black men who have sex with men and women (MSMW), concomitant with STI-to-PrEP interventions, will facilitate g... (10/14/2019)
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Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions 

Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions

JOURNAL OF VIROLOGY - Using samples from participants in the Multicenter AIDS Cohort study, Garcia-Bates, Palma, Shen, Gambotto, Macatangay, Ferris, Rinaldo, and Mailliard showed that PD-1 activation plays a positive role in initiating the primary T cell response. But later blocking of that pathway... (12/13/2018)

Development of antibody biomarkers of long term and recent dengue virus infections 

Development of antibody biomarkers of long term and recent dengue virus infections

JOURNAL OF VIROLOGICAL METHODS - BURKE, MARQUES, and colleagues discuss anti-dengue NS1-specific IgG and IgG3 as potential biomarkers of long-term and recent (less than 6 months) DENV infections, respectively.  (06/14/2018)

Tradition and innovation in development of a Zika vaccine 

Tradition and innovation in development of a Zika vaccine

THE LANCET - MARQUES and BURKE comment about two Zika vaccines in clinical development and describe the challenges ahead. (06/14/2018)

IDM Videos

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Amanpour & Salk: Vaccine lessons from history (video) 

Amanpour & Salk: Vaccine lessons from history (video)

CNN — Christiane Amanpour discusses with IDM's Peter Salk the 97% drop in polio prevalence within a few years of initial vaccine adoption. In 1953, Dr. Peter Salk was one of the first to receive a polio vaccine—from none other than his father, Jonas Salk. They go on to discuss herd immunity and vac... (01/13/2021)
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"It's going to be a long road" - What IDM's Peter Salk thinks about COVID-19 

"It's going to be a long road" - What IDM's Peter Salk thinks about COVID-19

USA TODAY - Jonas Salk’s vaccine helped wipe polio from most of the world, something that many people hope will happen with the coronavirus vaccine. However, IDM's Dr. Peter Salk warns eradicating polio from the U.S. was a long and difficult journey, and he doesn’t expect eliminating COVID-19 will ... (12/29/2020)
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Biden coronavirus task force appointee Michael Osterholm discusses "The COVID Pandemic: The Evolving Reality" (video) 

Biden coronavirus task force appointee Michael Osterholm discusses "The COVID Pandemic: The Evolving Reality" (video)

In a special IDM Seminar, Michael T. Osterholm answers questions regarding the epidemiology of SARS-CoV-2 infection, public health strategies to reduce transmission, and thoughts on how the world will likely look one year from now. Osterholm was recently appointed to President-elect Biden's coronav... (12/17/2020)

Q&A: Peter Salk on the Lessons Learned from Vaccine Development History 

Q&A: Peter Salk on the Lessons Learned from Vaccine Development History

Peter Salk was 11 years old when a University of Pittsburgh team led by his father, the late Jonas Salk, created the inactivated poliovirus vaccine. The day of the 1955 announcement that the vaccine was safe, effective and potent, “everything just went crazy,” he recalls. “There were so many calls ... (11/17/2020)
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HIV-related stigma in healthcare settings during COVID-19 

HIV-related stigma in healthcare settings during COVID-19

As part of the Conversations about COVID-19 seminar series, Mackey Friedman of IDM and BCHS joins IDM's Sarah Krier to discuss how the COVID-19 pandemic is affecting the lives of people living with HIV including their beliefs and attitudes about their healthcare needs and experiences. (10/16/2020)
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