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Rodriguez Serves on Raccoon Oral Rabies Vaccination Team

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As a participant in the Allegheny County Health Department’s Pittsburgh Summer Institute (ACHD PSI), Samantha Rodriguez (IDM '16) helped to plan, execute, and review the county’s Raccoon Oral Rabies Vaccination (ORV) Program, as well as assisted with ORV distribution. 

Lowery conducts West Nile Virus surveillance with ACHD

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Joel Lowery (IDM ’17) assisted the ACHD in conducting its annual surveillance of West Nile Virus (WNV) in order to make informed decisions on vector control related to mosquitoes. In addition to WNV, the team monitored Aedes albopictus , a possible mosquito vector for the Zika virus. Lowery was responsible for setting traps, entering data, and shipping samples to the Pennsylvania Department of Environmental Protection for testing. He took awa... 

There's No Vaccine Yet for CMV

Work on a vaccine for CMV has been going on for many years, said microbiologist Charles Rinaldo, PhD, an expert in cytomegalovirus in the Department of Infectious Diseases and Microbiology at Pitt Public Health. 

Revolutionary Acts: How the discussion of HIV risk matters for the health of Black men who have sex with men

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Derrick D. Matthews, assistant professor in the University of Pittsburgh Graduate School of Public Health’s Department of Infectious Diseases and Microbiology, focuses his research upon the disproportionate burden the HIV epidemic has on black gay, bisexual and other men who have sex with men (MSM) in the U.S....  

Doctor returns to Pittsburgh after trip To Brazil to study Zika virus

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PITTSBURGH (KDKA) — Ernesto Marques at the Pitt Center for Vaccine Research  recently traveled to Brazil  to study  Zika virus . In that time, the CDC announced a definitive relationship between Zika and microcephaly based on the timing, the virus in fluids and tissues, antibodies against the virus in the brains of these babies with small heads, and studies of cases and non-cases.   See full story  

The Pittsburgh AIDS Task Force Celebrates 30 Years

The event honored Dr. Anthony Silvestre, who since 1984 has been involved in LGBTQ health and HIV prevention services and research.  

Center for Mindfulness and Consciousness Studies

Mindfulness enhances one's concentration, reduces stress, and, in general, improves cognitive skills. 

Pitt Professor Awarded $6.4 Million for Cancer Research

Dr. Patrick Moore is one of only 60 people in the country to receive the Outstanding Investigator Award from the National Cancer.  

Roaming Photo-Story Exhibit Brings ‘Acceptance Journeys Pittsburgh’ to Campus

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A free exhibit called “Acceptance Journeys Pittsburgh” will be popping up throughout the University of Pittsburgh campus over the next several weeks, spreading a message of love and support for lesbian, gay, bisexual and transgender (LGBT) people.Conducted by the Department of Infectious Disease and Microbiology at Pitt’s Graduate School of Public Health, the exhibit is a part of Pitt’s “Year of the Humanities” and addresses LGBT stigma through s... 

Pitt researcher heads to Brazil to study Zika virus

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PITTSBURGH (KDKA) – Brazil is at the center of concern over the Zika virus and a researcher from this area is starting his work there today. From the Pitt Center for Vaccine Research to Brazil, Dr. Ernesto Marques is making an important trip.  “The health authorities were expecting in 2015 either a dengue or chikungunya outbreak, and something else came up, with very unexpected consequences that at the beginning, no one imagined that was a ... 

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Recent IDM Publications

Rift Valley fever in animals and humans: Current perspectives 

Rift Valley fever in animals and humans: Current perspectives

ANTIVIRAL RESEARCH - McMillen and Hartman discuss the historical role of Rift Valley Fever (RVF) as a biological weapon and conclude with an outline of the important unanswered questions for ongoing research into this important zoonotic disease. (06/11/2018)

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN 

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN

JOURNAL OF VIROLOGY - Delucia, Rinaldo, Rappocciolo demonstrate that the use of SIMV to decrease macrophage-mediated virus transfer should be considered for future HIV therapeutic development.  (05/18/2018)

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury 

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury

JOURNAL OF NEUROINFLAMMATION - Guha, Wagner, Ayyavoo conduct first study evaluating the potential role of Ng in the context of HIV-1 neropathogens and conclude that synaptic damage in HAND+ patients could be a result of abrogation of Ng through HIV-1 induced inflammation that dysregulates Ng-CaM in... (05/18/2018)

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques 

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques

JOURNAL OF IMMUNOLOGY - Wonderlich, Swan, Bissel, Hartman, Carney, O'Malley, Obadan, Santos, Walker, Sturgeon, Frye, Maiello, Scanga, Bowling, Duangkhae, Wiley, Flynn, Wang, Cole, Reed, Barratt-Boyes establish a new nonhuman primate disease model for evaluation of vaccine and therapeutic approaches... (02/14/2018)

Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4+ T cells 

Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4+ T cells

NATURE MEDICINE - Gupta, Sanyal, Ratner, Ding, Zerbato, Giacobbi, Venkatachari, Patterson, Chargin, Chen, Mailliard, Rinaldo, and Sluis-Cremer found that the size of the inducible latent HIV-1 reservoir in aviremic subjects on ART is approximately 70-fold larger than previous estimates.  (02/08/2018)

Peripheral blood biomarkers of disease outcome in a monkey model of rift valley fever encephalitis.  

Peripheral blood biomarkers of disease outcome in a monkey model of rift valley fever encephalitis.

JOURNAL OF VIROLOGY - Wonderlich, Caroline, McMillen, Walters, Reed, Barratt-Boyes, and Hartman conclude that African green monkeys are a novel and suitable model for studying the neuropathogenesis of Rift Valley Fever (RVF) and for testing vaccines and therapeutics against this important emerging ... (02/05/2018)

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