TIMES OBSERVER - Pitt scientists have discovered the fastest way to identify potent, neutralizing human monoclonal antibodies against SARS-CoV-2. When Chinese scientists published the virus' genetic sequence January, Dimitrov’s team rapidly generated the virus’s receptor binding domain-part of the spike protein that attaches to human cells-and used it as “bait” to pan their multiple libraries of over 1 trillion human antibodies built over preced...
As part of the Conversations about COVID-19 seminar series, Mackey Friedman of IDM and BCHS joins IDM's Sarah Krier to discuss how the COVID-19 pandemic is affecting the lives of people living with HIV including their beliefs and attitudes about their healthcare needs and experiences.
THE CONVERSATION - Respiratory scientist Douglas Reed, IDM and Pitt Med, examined studies that have shown how the virus has spread, including at a call center in South Korea, a restaurant in China, and a choir practice in Washington state. “The evidence strongly suggests that airborne transmission happens easily and is likely a significant driver of this pandemic. It must be taken seriously as people begin to venture back out into the world.”
CUMBERLAND TIMES-NEWS - IDM’s John Mellors, UPMC’s chief of infectious diseases, said the biological molecule “is small, which means it penetrates into areas of the body where a full-sized antibody may not. It’s fully human, meaning that there’s no foreign material that’s likely to be rejected by the host… and it appears to be safe.” But he added, it's too early to talk about pricing of a treatment when it’s not (tested) in humans yet.
What we have learned during the summer of 2020 that puts SARS-CoV-2 into perspective with other emerging viruses and explores the current state of COVID-19 forecasting for the next few months. IDM's Amy Hartman talks what we know (and don't know) about SARS-CoV-2 and EPI's Donald Burke discusses the epidemiological and environmental factors that will shape the likely phases of the epidemic in our region.
PSI students Matt Duespohl (IDM ‘20) and Annette Curry (IDM ’21) had the opportunity to volunteer for the annual oral rabies baiting that occurred the first week of August in southwestern Pennsylvania. Since 2001, ACHD has partnered with the USDA Wildlife Services each summer to distribute hundreds of thousands of oral raccoon rabies vaccine baits across Allegheny County by hand. To learn more about how the program impacts local wildlife from pr...
NEXT PITTSBURGH - Allegheny County, like Minneapolis, has substantial racial disparities that impact all of us. Our communities are starkly divided along racial and ethnic lines. With these lines come distinct differences in access to housing, education, transportation and employment. These differences translate directly to worse health outcomes among our communities of color. In Allegheny County, black people have dramatically higher rates of b...
NPR - If you want to exercise indoors, it’s safer to do it at home, says IDM’s Doug Reed, an immunologist and aerobiologist. If you do go to the gym and you’re breathing heavily, it would be better to double your regular physical distance to 12 feet, because we don’t know exactly how far virus particles travel when people are breathing heavily. The potential for being infected or spreading the infection could be much higher.
PITTSBURGH POST-GAZETTE – The study is plausible, says IDM’s Giovanna Rappocciolo, but “rough around the edges”— a situation that could be remedied through the peer-review process. "If the research is verified, then COVID-19 potentially could be treated by manipulating cholesterol levels, with drugs already available. “It opens up a new field of study to try to exploit these pathways to stop the infection of cells.”
Congratulations to Justin A. Dutta (IDM '19, HUGEN '23) who was recently awarded a Critical Languages Scholarship from the U.S. Department of State to study Portuguese. With an acceptance rate of less than 10%, the Critical Language Scholarship is one of the country's most competitive scholarships and the most prestigious language program for U.S. citizens.