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Three MPH students selected for the Milken Institute's Health Leaders Program

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The Milken Institute is a nonprofit, nonpartisan think tank determined to increase global prosperity by advancing collaborative solutions that widen access to capital, create jobs, and improve health. In 2018, they launched the Future Health Leaders Pilot Program to create the right connections between organizations, students, and schools. Students chosen this year from Pitt Public Health are KAITLYN SAAL-RIDPATH (JD/MPH ’20), JESSICA SALERNO (I... 

Celebrate 70: DeLucia presents cholesterol regulation of HIV-1 trans infection and HIV-1 disease progression (VIDEO)

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Doctoral candidate, DIANA DeLUCIA (IDM '19), presented some of her dissertation research on how the cholesterol levels in immune cells might be impacting HIV infection and disease progression to AIDS. It was found that antigen-presenting cells in nonprogressors have lower cholesterol levels which is associated with their inability to pass virus on to other cells.   

Celebrate 70: Global health impact (video)

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Faculty and alumni spoke on a panel to highlight the public health impact on global communities, including immigration crises, planetary health, climate change, and the importance of health systems. KELLY SALDANA (BCHS ’01) talked about creating resiliency and figuring out what that means both at the individual level and the systems level to help lessen negative effects of climate change.  

Perkins invited back to present at IDM Seminar Series

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Douglas J. Perkins, a former assistant professor in IDM (2001-2007), was invited back to present at the IDM Seminar Series on March 28. His presentation was on "Genomic Approaches for Uncovering the Pathogenesis of Severe Malarial Anemia in African Children."  

Salerno selected for summer program in Colombia

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JESSICA SALERNO (IDM '20) has been selected to participate in Red Tree Study's Academic Summer Program at the Institute of Public Health at Pontificia Universidad Javeriana in Bogota, Colombia. In this program, students learn from experts while helping to ensure the health of Colombian citizens as the country transitions towards peace.   

Rappocciolo presents research on cell cholesterol dysregulation in HIV non-progressors at 2018 Conference on Retroviruses and Opportunistic Infections

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IDM's GIOVANNA RAPPOCCIOLO presented at the Conference on Retroviruses and Opportunistic Infections ion biomarkers and genetics of cell cholesterol dysregulation in HIV non-progressors. Co-authors include IDM faculty J MARTINSON and C RINALDO and recent doctoral graduate DIANA DELUCIA.   

Melody receives postdoctoral fellowship

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University of Texas Medical Branch-Galveston has offered KEVIN MELODY (IDM '17) a postdoctoral fellowship in a BSL-4 research group headed by Thomas Geisbert. Due to the security and proficiency needed to perform the work, Kevin will undergo extensive training before beginning high-containment pathogen-related research.  

Swan joins Cato Research

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"A great company in a great industry," says ZACHARY SWAN (IDM '16) who has recently secured a position as a Regulatory Affairs, Clinical Strategy Scientist at a CRO in the Research Triangle Park named Cato Research.  

Emerson Evans on detail with CDC

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Helping out with The United States President's Emergency Plan for AIDS Relief (PEPFAR) Country Operational Plan submission, EMERSON EVANS (IDM '12) is currently working in South Africa on detail with the CDC. 

Poston receives San-Pin Wang Award from the Chlamydia Basic Research Society

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The San-Pin Wang Award for the best graduate student oral presentation at the Chlamydia Basic Research Society 2017 conference was given to TAYLOR POSTON (IDM '17). This award was established in honor of the memory of Dr. San-Pin Wang and a cash prize was generously donated by the San-Pin Wang Endowment Fund.  

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Recent IDM Publications

Development of antibody biomarkers of long term and recent dengue virus infections 

Development of antibody biomarkers of long term and recent dengue virus infections

JOURNAL OF VIROLOGICAL METHODS - BURKE, MARQUES, and colleagues discuss anti-dengue NS1-specific IgG and IgG3 as potential biomarkers of long-term and recent (less than 6 months) DENV infections, respectively.  (06/14/2018)

Tradition and innovation in development of a Zika vaccine 

Tradition and innovation in development of a Zika vaccine

THE LANCET - MARQUES and BURKE comment about two Zika vaccines in clinical development and describe the challenges ahead. (06/14/2018)

Zika virus displacement by a chikungunya outbreak in Recife, Brazil 

Zika virus displacement by a chikungunya outbreak in Recife, Brazil

PUBLIC LIBRARY OF SCIENCE - Magalhaes, Braga, Cordeiro, Oliveira, Castanha, Maciel, Amancio, Gouveia, Peixoto-deSilva Jr., Peixoto, Britto, Lima, Lima, and Marques detected the tail end of a Zika epidemic in 2015-16 which was displaced by a chikungunya epidemic. Few dengue cases were identified des... (06/14/2018)

Rift Valley fever in animals and humans: Current perspectives 

Rift Valley fever in animals and humans: Current perspectives

ANTIVIRAL RESEARCH - McMillen and Hartman discuss the historical role of Rift Valley Fever (RVF) as a biological weapon and conclude with an outline of the important unanswered questions for ongoing research into this important zoonotic disease. (06/11/2018)

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN 

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN

JOURNAL OF VIROLOGY - Delucia, Rinaldo, Rappocciolo demonstrate that the use of SIMV to decrease macrophage-mediated virus transfer should be considered for future HIV therapeutic development.  (05/18/2018)

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury 

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury

JOURNAL OF NEUROINFLAMMATION - Guha, Wagner, Ayyavoo conduct first study evaluating the potential role of Ng in the context of HIV-1 neropathogens and conclude that synaptic damage in HAND+ patients could be a result of abrogation of Ng through HIV-1 induced inflammation that dysregulates Ng-CaM in... (05/18/2018)

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques 

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques

JOURNAL OF IMMUNOLOGY - Wonderlich, Swan, Bissel, Hartman, Carney, O'Malley, Obadan, Santos, Walker, Sturgeon, Frye, Maiello, Scanga, Bowling, Duangkhae, Wiley, Flynn, Wang, Cole, Reed, Barratt-Boyes establish a new nonhuman primate disease model for evaluation of vaccine and therapeutic approaches... (02/14/2018)

Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4+ T cells 

Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4+ T cells

NATURE MEDICINE - Gupta, Sanyal, Ratner, Ding, Zerbato, Giacobbi, Venkatachari, Patterson, Chargin, Chen, Mailliard, Rinaldo, and Sluis-Cremer found that the size of the inducible latent HIV-1 reservoir in aviremic subjects on ART is approximately 70-fold larger than previous estimates.  (02/08/2018)

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IDM Videos

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IDM’s Rinaldo discusses HIV wonder drugs and curing HIV in 1998 World AIDS Day interview (VIDEO) 

IDM’s Rinaldo discusses HIV wonder drugs and curing HIV in 1998 World AIDS Day interview (VIDEO)

UPMC HEALTH NEWS – In the late 1990s, new and highly potent anti-HIV drugs emerged— including protease and reverse transcriptase inhibitors—which could for the first time control HIV infection. For this 1998 World AIDS Day, Pitt IDM AIDS researcher Charles Rinaldo and the late Bridget Murtagh of th... (07/17/2018)
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Matthews on why we need a public health approach to HIV (video) 

Matthews on why we need a public health approach to HIV (video)

IDM's DERRICK MATTHEWS explains Pitt Public Health's work on HIV/AIDS and where we are today. "If your’e a black gay man in the U.S., you have a one in two change in your lifetime of becoming HIV positive…short of the cure that we’re looking for, the biology is way ahead of the social implementat... (06/20/2018)
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Matthews discusses the fields of infectious diseases and microbiology (IDM) (video) 

Matthews discusses the fields of infectious diseases and microbiology (IDM) (video)

IDM's DERRICK MATTHEWS demystifies infectious diseases and microbiology with a basic overview of the fields, how they are practiced, and how disease is spread.  (06/19/2018)
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Celebrate 70: DeLucia presents cholesterol regulation of HIV-1 trans infection and HIV-1 disease progression (VIDEO) 

Celebrate 70: DeLucia presents cholesterol regulation of HIV-1 trans infection and HIV-1 disease progression (VIDEO)

Doctoral candidate, DIANA DeLUCIA (IDM '19), presented some of her dissertation research on how the cholesterol levels in immune cells might be impacting HIV infection and disease progression to AIDS. It was found that antigen-presenting cells in nonprogressors have lower cholesterol levels which i... (04/19/2018)
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