University of Pittsburgh Directory Calendar News Careers Alumni Giving

Search
  • Home
  • Behavioral and Community Health Sciences
  • Biostatistics
  • Environmental and Occupational Health
  • Epidemiology
  • Health Policy and Management
  • Human Genetics
  • Infectious Diseases and Microbiology
    • Academics

      • MPH, PEL
      • MPH, MIC
      • MS
      • PhD
      • Certificates
      • Courses
        • Class Schedule
      • Student Handbooks & Forms
    • Research & Practice

      • Centers Overview
        • MidAtlantic AIDS Education and Training Center
        • HIV Prevention and Care Project
        • Pitt Men's Study
      • Faculty Research
        • Fogarty AIDS Research and Training Program in India
      • Student Research
    • Admissions & Aid

      • Admissions
      • Financial Aid
      • Request Information
      • Apply Now
    • Seminars & Events

      • IDM Events
      • IDM Seminar Series
      • IDM MPH Journal Club
      • IDM PhD & MS Journal Club
      • IDM Dissertation Defenses
      • IDM Master's Defenses
      • IDM Annual Research Day
    • Who's Who

      • Faculty (All)
        • Primary Faculty
        • Secondary Faculty
        • Adjunct Faculty
        • Emeritus and Retired Faculty
      • Staff (All)
      • Postdoctoral Researchers
      • Contact Us
    • About

      • Welcome from Chair
      • History
      • Mission
      • Strategic Plan
      • Alumni
      • IDM Department News
        • IDM Faculty News
        • IDM Student Stories
        • IDM Alumni Stories
        • Social Media
        • Newsletters
      • Bob Yee Scholars
  • Academics
    • MPH, PEL
    • MPH, MIC
    • MS
    • PhD
    • Certificates
    • Courses
      • Class Schedule
    • Student Handbooks & Forms
  • Research & Practice
    • Centers Overview
      • MidAtlantic AIDS Education and Training Center
      • HIV Prevention and Care Project
      • Pitt Men's Study
    • Faculty Research
      • Fogarty AIDS Research and Training Program in India
    • Student Research
  • Admissions & Aid
    • Admissions
    • Financial Aid
    • Request Information
  • Seminars & Events
    • IDM Events
    • IDM Seminar Series
    • IDM MPH Journal Club
    • IDM PhD & MS Journal Club
    • IDM Dissertation Defenses
    • IDM Master's Defenses
    • IDM Annual Research Day
  • Who's Who
    • Faculty (All)
      • Primary Faculty
      • Secondary Faculty
      • Adjunct Faculty
      • Emeritus and Retired Faculty
    • Staff (All)
    • Postdoctoral Researchers
    • Contact Us
  • About
    • Welcome from Chair
    • History
    • Mission
    • Strategic Plan
    • Alumni
    • IDM Department News
      • IDM Faculty News
      • IDM Student Stories
      • IDM Alumni Stories
      • Social Media
      • Newsletters
    • Bob Yee Scholars
Apply Now

IDM Events

IDM Departmental Calendar

Event
Mon 12/16/2019 12:00PM - 1:00PM
IDM Event
IDM Seminar (Leah Katzelnick, PhD) IDM Event
IDM Seminar (Leah Katzelnick, PhD)
Mon 12/16/2019 12:00PM - 1:00PM
Public Health Lecture Hall (A115)


Public Health Lecture Hall (A115)

Recent Events

IDM Master's Defense

Jen Burwinkel - MS '18: Using Tissue Culture to Model Early Events in Francisella tularensis...

  Email this event to me @

Friday 4/6 10:00AM - 12:00PM
A425 Public Health

Using Tissue Culture to Model Early Events in Francisella tularensis Pathogenesis

Abstract: Francisella tularensis is a highly infectious bacterium that causes tularemia or rabbit fever. The infectious dose is as low as 10 CFU. While a lot of F. tularensis research focuses on macrophages, lung epithelium cells may be important too. There are far more epithelial cells on the surface of the lungs than macrophages. With such a low infectious dose, it is more likely for F. tularensis to infect an epithelial cell than macrophage. I found that F. tularensis has similar growth rates in human alveolar epithelial cells (A549) as murine macrophages (J774) after initial infection. Also, I have demonstrated that F. tularensis can infect human primary bronchial epithelium (HBE) in a 3D culture system that mimics airway architecture in the lung. The data suggests that it takes F. tularensis longer to infect the HBE cells than the A549 or J774 cells. I have worked to develop a protocol for infecting HBE cells with F. tularensis. The pathogenesis in rabbit lung tissue was assessed too. Over the course of the first three days post-exposure there is an increasing amount of inflammation, hemorrhaging and apoptosis in the lower left lung of rabbits. When taken all together, this data suggests lung epithelial cells could have a role in F. tularensis early pathogenesis and dissemination. 

Advisor: Douglas Reed

 

Enrolled Users:

Last Updated On Thursday, April 5, 2018 by Abby Kincaid
Created On Tuesday, April 3, 2018

  • Return
  • Export
NovDecember 2019Jan
SunMonTueWedThuFriSat
12
1 Event(s)
34
2 Event(s)
567
89
1 Event(s)
1011121314
1516
1 Event(s)
1718192021
22232425262728
2930311234
567891011

View more events at Pitt Public Health

  • FULL SCHOOL CALENDAR
  • LCD screens (scrolling events)
  • The Week Ahead 
  • Grand Rounds
  • Student organization events
  • Food For Thought
  • One Book, One Community
  • Dissertation defenses
  • CPH continuing education
  • Academic calendar
  • Graduation deadlines
  • Professional Development
  • Career Services events and
    Pitt Bridges
  • Governance Meetings
  • Alumni Events

Submit events and news

Click to enter calendar events or share school news and announcements.

Back to Top

Map-Parran Hall, Pittsburgh, PA

Pitt Public Health
130 De Soto Street
Pittsburgh, PA 15261 USA

Contact Us
Prospective Students
What is Public Health?
Why Pitt Public Health?
Academics
Student Life
Admissions

Governance
Delta Omega
Resources
For Employers
Open Positions

Update Your Profile

Technology Support
Technology Policies

Communications Tools
and Samples
CEPH
© 2019 by University of Pittsburgh Graduate School of Public Health

Login  |  Sitemap