IDM Events

IDM Departmental Calendar

Event
Wed 7/15/2020 12:00PM - 1:00PM
MidAtlantic AIDS Education and Training Center Webinar/Online Event
Accessing Pre-Exposure Prophylaxis (PrEP): Billing and Coding MidAtlantic AIDS Education and Training Center Webinar/Online Event
Accessing Pre-Exposure Prophylaxis (PrEP): Billing and Coding
Wed 7/15/2020 12:00PM - 1:00PM
** Online/Virtual Event **

The purpose of this webinar is to describe the process of coding for PrEP in WV and PA, discuss the implementation of billing for PrEP, and compare the different options for paying for PrEP.


** Online/Virtual Event **
Mon 7/20/2020 11:00AM - 12:00PM
MidAtlantic AIDS Education and Training Center Webinar/Online Event
Virtual HIV in West Virginia: Tackle the Epidemic, Not the Opioids MidAtlantic AIDS Education and Training Center Webinar/Online Event
Virtual HIV in West Virginia: Tackle the Epidemic, Not the Opioids
Mon 7/20/2020 11:00AM - 12:00PM
** Online/Virtual Event **

This webinar will focus on the question of why there is a raging epidemic of addiction. The current opioid epidemic is a symptom of the fraying of the socio-economic fabric of rural United States. We will also look at the reasons why funding should be targeted to substance misuse, not to the drug of the moment.


** Online/Virtual Event **
Tue 7/21/2020 9:00AM - 10:00AM
MidAtlantic AIDS Education and Training Center Webinar/Online Event
Special Populations in Ending the HIV Epidemic: Routine HIV Testing in Adolescents MidAtlantic AIDS Education and Training Center Webinar/Online Event
Special Populations in Ending the HIV Epidemic: Routine HIV Testing in Adolescents
Tue 7/21/2020 9:00AM - 10:00AM
** Online/Virtual Event **

At the end of the webinar, participants will be able to describe current guidelines and epidemiology for HIV testing among adolescents, identify key steps in educating health professionals on routine HIV testing for adolescents, and discuss lessons learned and how to implement these lessons learned across EHE regions.


** Online/Virtual Event **
Thu 7/23/2020 2:00PM - 3:00PM
MidAtlantic AIDS Education and Training Center Webinar/Online Event
Telehealth and Pre-Exposure Prophylaxis (PrEP) during COVID-19 MidAtlantic AIDS Education and Training Center Webinar/Online Event
Telehealth and Pre-Exposure Prophylaxis (PrEP) during COVID-19
Thu 7/23/2020 2:00PM - 3:00PM
** Online/Virtual Event **

This session will describe PrEP and the importance of adherence during the COVID-19 pandemic, barriers to PrEP that have been brought on by COVID-19, strategies to overcome barriers and promote adherence, and how telehealth can be used to promote PrEP.


** Online/Virtual Event **
Thu 7/30/2020 2:00PM - 3:00PM
MidAtlantic AIDS Education and Training Center Webinar/Online Event
Roadmap for COVID-19 Vaccine Development MidAtlantic AIDS Education and Training Center Webinar/Online Event
Roadmap for COVID-19 Vaccine Development
Thu 7/30/2020 2:00PM - 3:00PM
** Online/Virtual Event **

This webinar will describe the process of vaccine development during COVID-19 and discuss the challenges and opportunities associated with vaccine development.


** Online/Virtual Event **

Recent Events

IDM Dissertation Defense

Lyndsay Avery - PhD '18: Tim-3 co-stimulation promotes short-lived effector T cells, restricts...

Wednesday 4/25 9:00AM - 11:00AM
Scaife Hall

Tim-3 co-stimulation promotes short-lived effector T cells, restricts memory precursors, and is dispensable for T cell exhaustion

Abstract: Tim-3 is highly expressed on a subset of T cells during T cell exhaustion, in settings of chronic viral infection and tumors. Using LCMV Clone 13, a model for chronic infection, we have found that Tim-3 is neither necessary nor sufficient for the development of T cell exhaustion. Nonetheless, expression of Tim-3 was sufficient to drive resistance to PD-L1 blockade therapy during chronic infection. Strikingly, expression of Tim-3 promoted development of short-term effector T cells, at the expense of memory precursor development, after acute LCMV infection. These effects were accompanied by increased Akt/mTOR signaling in T cells expressing endogenous or ectopic Tim-3. Conversely, Akt/mTOR signaling was reduced in effector T cells from Tim-3 deficient mice. Thus, Tim-3 is essential for optimal effector T cell responses, but may also contribute to exhaustion, by restricting development of long-lived memory T cells. Taken together, our results suggest that Tim-3 is actually more similar to co-stimulatory receptors that are upregulated after T cell activation, rather than a dominant inhibitory protein like PD-1. These findings have significant implications for the development of anti-Tim-3 antibodies as therapeutic agents. 

Mentor: Lawrence Kane, PhD (Mentor)
Advisor: Charles Rinaldo, PhD (Chair)

Last Updated On Friday, March 30, 2018 by Abby Kincaid
Created On Wednesday, March 7, 2018

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