Journal Club (Spring)

Journal Club

The Human Genetics Journal Club meets weekly on Fridays each spring, from 1:30-2:30 p.m. in A215 Public Health. Journal club starts promptly at 1:30, and discussion is cut off at 2:30. Papers and presenters are listed below. Students who are taking journal club for credit should see Courseweb for a full syllabus and assignments.

Minimize Spring 2020 meetings

1/17/20 • Nauman Ahmad
Lerchenmueller et al. Gender differences in how scientists present the importance of their research: observational study. BMJ 2019;367l6573. doi: 10.1136/bmj.l6573

1/24/20 • Jordan Harper
Zhou et al. Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo. Hum Mol Genet 2019; 28:1971-1981

1/31/20 • Lindsey Spiker
Ramos-Rodriguez et al. The impact of proinflammatory cytokines on the beta-cell regulatory landscape provides insight into the genetics of type 1 diabetes. Nature Genet 2019; 51:1588-1595

2/7/20 • Tianyu Zou
Nath et al. Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological, and cardiometabolic pleiotropy. Am J Hum Genet 2019; 105:1076-1090

2/14/20 • Laura Savariau
Xu et al. ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer. Nature Genet 2020;

2/21/20 • Yulong Bai
Sarnowski et al. Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: the trans-omics for precision medicine program. Am J Hum Genet 2019; 105:706-718

2/28/20 • Talia Oranburg
Yattah et al. Dynamic lamin B1-gene association during oligodendrocyte progenitor differentiation. Neurochem Res 2020; doi: 10.1007/s11064-019-02941-y. [Epub ahead of print]

Note that the subsequent journal club meetings will be held remotely, through Zoom.

If you are not registered for the course, but are interested in participating, email to to obtain the Zoom contact details. 

3/27/20 • Vaishali Muralidaran
LaCroix et al. GGC repeat expansion and exon 1 methylation of XYLT1 is a common pathogenic variant in Baratela-Scott syndrome.

4/3/20 • Gillian Goobie
Gondalia et al. Methylome-wide association study provides evidence for particulate matter air pollution-associated DNA methylation. Environ Int. 2019; 132:104723.

4/10/20 • Alayna Holderman
Du et al. Polycomb group proteins regulate chromatin architecture in mouse oocytes and early embryos. Mol Cell. 2020; 77:825-839.



Contact Zsolt Urban (

Journal Club "Rules and Regulations"

  • The goal of journal club is to provide an informal venue for scientific interaction in the Department of Human Genetics.  
  • Students are advised to get advice from a faculty member when choosing a paper to present. The ideal journal club article is something that is of both scientific importance and general interest.
  • Let the faculty facilitator (Zsolt Urban) know what your choice is 2 weeks before your presentation so that the link can be posted on the web site.
  • IF YOU NEED TO CANCEL OR RESCHEDULE a presentation, it is YOUR responsibility to find a substitute.
  • Please let the faculty facilitator know if you need a laptop or other media needs.
  • Presentations should begin with an introduction to the general topic area and what is interesting or important about the work being presented. Try to explain key concepts and definitions. Do not assume everyone in the audience is an expert or that everyone in the audience has read the paper.