Hyun Jung (HJ) Park, PhD

Assistant Professor, Human Genetics

Assistant Professor, Biostatistics

Contact

3122 Public Health Building, 130 DeSoTo street, Pittsburgh, PA 15216
R-znvy: ulc60@cvgg.rqh
Primary Phone: 967-838-5075
Web site:


Personal Statement

Our Vision: A.I. Meets Biology

We develop data-science techniques, AI-driven tools, and statistical inference methods to understand large-scale molecular dynamics in physiological and pathological conditions hidden in various biological layers. Based on the knowledge of the dynamics, we collaborate with clinicians to develop 'precision medicine' clinical strategies for patients.


Education

2017 Postdoc Associate, Duncan Cancer Center (Wei Li, mentor), Baylor College of Medicine

2012 Ph.D., Computer Science (Luay Nakhleh, mentor), Rice University

2007 M.S., Computer Science (Tiffani Williams, mentor), Texas A&M University

2005 B.S., Computer Science, Yonsei University


Teaching

HUGEN 2073 Genomic Data Visualization & Annotation

HUGEN 2072 Genomic Data Pipelines And Tools


Selected Publications

S. Kim^, Y. Bai, Z. Fan, B. Diergaarde, G. C. Tseng, H-J. Park*, The microRNA target site landscape is a novel molecular feature associating alternative polyadenylation with immune evasion activity in breast cancer. Briefings in Bioinformatics (2020), bbaa191 

H-J. Parkˆ, P. Jiˆ, S. Kim, Z. Xia, B. Rodriguez, C-P. Masamha, A-B, Shyu, J. Neilson, E.J. Wagner*, W. Li*, “3′ UTR shortening Down-regulates Tumor Suppressors in trans by Disrupting the CeRNA Crosstalk." Nature Genetics, 50, 783-789 (2018). DOI:10.1038

H. J. Park^*, S. Kim, W. Li*, “Model-based analysis of competing-endogenous pathways
(MACPath) in human cancers”, PLoS Computational Biology, 14(3): e1006074. DOI:10.1371.

M. Jeong^, H. J. Park^, H. Celik, E. L. Ostrander, J. M. Reyes, A. Guzman, B. Rodriguez, Y. Lee, L. Ding, O. A. Guryanova, W. Li, M. A. Goodell*, G. A. Challen*, “Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells in vivo”, Cell Reports, in press.

L. Minˆ, M. Jeongˆ, D. Sunˆ, H-J. Parkˆ, B. Rodriguezˆ, Z. Xia, L. Yang, X. Zhang, GJ. Darlington, W. Li* and M.A. Goodell*, “Long Non-coding RNAs Control Hematopoietic Stem Cell (HSC) Function." Cell Stem Cell, 16(4):426-38, 2015. DOI:10.1016/j.stem.2015.02.002 

L. Wangˆ, H-J. Parkˆ, S. Wang, J-P Kocher, W. Li*, “CPAT: Coding-Potential Assessment Tool Using an Alignment-Free Logistic Regression Model." Nucleic Acid Research 41(6), 2013, DOI:10.1093/nar/gkt006 
H-J. Parkˆ and L. Nakhleh*, “Inference of Reticulate Evolutionary Histories by Maximum Likelihood: The Performance of Information Criteria." BMC Bioinformatics, 13: S12, 2012. bmcbioinformatics.biomedcentral.com/articles 








 

Hyun Jung (HJ)  Park