Elsa S. Strotmeyer, PhD, MPH

Dr. Strotmeyer is a tenured Associate Professor in the Department of

Epidemiology and a Co-Director of the NIA T32 Epidemiology of Aging Training Grant at the University of Pittsburgh, where she completed her MPH (1997), PhD in Epidemiology (2000), and a subsequent NIA T32 Post-Doctoral Fellowship (2001-2003). She is an expert in the area of the epidemiology of aging with research that focuses on metabolic risk factors and diabetes-related conditions in aging associated with neuromuscular and musculoskeletal declines in the etiology of fall injuries, mobility, disability and mortality. Dr. Strotmeyer has contributed to the field of aging research through pioneering work on the complex inter-relationships of peripheral nerves, neuromuscular and musculoskeletal function in aging and diabetes. Her recent studies include evaluation of risk factors for neuromuscular and musculoskeletal decline in the pathway to fall injuries and mobility disability. She has received >$5 million of direct external funding from federal and professional organizations, published over 160 original articles, and was awarded several prestigious honors including an invited lectureship, the 2007 Health Sciences Research Award from the Gerontological Society of America (GSA), and Fellowship in the GSA and American Society for Bone and Mineral Research (ASBMR) for her research. Her research addressing the importance of peripheral nerve and neuromuscular impairments in aging and diabetes, demonstrated high rates of impairment which are critical to lower extremity performance, bone loss, falls and fracture. In older adults, she found that peripheral nerve impairments result in a 2-fold increased risk of mobility limitation which is independent of diabetes and account for approximately 25% of poor performance in older adults with diabetes. Dr. Strotmeyer also made major contributions to the understanding of osteoporosis and fracture in diabetes. Her work showing that type 2 diabetes is associated with 64% higher fracture risk, independent of the generally higher bone mineral density (BMD) and higher weight in older adults with type 2 diabetes has been cited >400 times. She was the first to find that bone loss was related to poor peripheral nerve function and is Multi-PI of an R01 to investigate detailed muscle associations with HRpQCT bone parameters in the Study of Muscle, Mobility and Aging (SOMMA). Her R01 using cohort and Medicare Fee-For-Service (FFS) data has created algorithms for fall injuries in claims. These findings led to a current R01 examining time trends for incident non-fracture fall injuries (NFFI) and fractures, across 20 years of 4 pooled longitudinal cohorts with ~12,000 women and men in Medicare FFS, a third of which are minority older adults; and will determine if incident NFFI predict future risk of major geriatric outcomes. Her ongoing work includes novel methods to assess leg power capturing neuromuscular function; physical activity interventions to improve neuromuscular function in older adults; and cross cohort epidemiologic studies. Overall, her public health and research goals are to prevent or delay poor health and functional outcomes in diabetes and aging, and ultimately to provide recommendations for improving health in older adults.

Dr. Strotmeyer has had substantial roles in teaching and service. She is the current Director of the T32 Epidemiology of Aging Training Program. She served as the Health Sciences past Chair of the Gerontological Society of America (GSA) in 2020-2021 after 2 years as Chair. She served on the Advocacy & Science Policy Committee of the ASBMR (2018-2021). Since 2016, she has been Co-Chair of the Cross Cohort Collaboration (CCC) Steering Committee, which promotes scientific collaboration across approximately 20 NIH-funded cohorts. Dr. Strotmeyer is an Associate Editor for the Journal of Gerontology: Medical Sciences and an Editorial Board member for Women’s Midlife Health. She was Editor of Clinics of Geriatric Medicine “Diabetes and Aging” 2015 issue and Co-Editor of the Women’s Midlife Health 2020 special issue on disability. She is the primary instructor of the Epidemiology of Aging Methods, which covers methodological aspects of epidemiologic research in aging as well as a field work component, and Epidemiology of Aging Workshop graduate courses for students in the health sciences. Dr. Strotmeyer initiated the Epidemiology of Aging Workshop to provide opportunities to apply concepts in the aging field through presentations of trainees’ in-progress research, critique of current articles in the field - particularly methods and statistical techniques, and practical professional skills such as manuscript review and career development skills. Dr. Strotmeyer has been as primary mentor and committee chair for 10 PhD students, of which 7 were awarded positions on the T32 training grant, 2 post-doctoral associates, and as co-mentor for 8 other PhD students. She is a voting member of the Pitt Public Health Educational Policies and Curriculum Committee (EPCC). In her Department, Dr. Strotmeyer is a member of the Curriculum Committee (Chair, 2018-2021), with decades of past service on multiple committees. Her service at the University Senate and Provost Office level has been extensive, with the goal of improving university benefits and welfare, focusing on equity issues. Dr. Strotmeyer’s teaching and service goals encompass multidisciplinary collaboration to promote the work of the next generation and foster translational and innovative research to ensure that every older adult has the opportunity to age well.

• Colgate University - B.A. Pre-health sciences/English literature, 1995 
• University of Pittsburgh - M.P.H. Epidemiology, 1997 
• University of Pittsburgh - Ph.D. Epidemiology, 2000

2007-2010, 2012-current
Epidemiology 2981: Epidemiology of Aging Methods

2014-current
Epidemiology 2950: Epidemiology of Aging Workshop

2007
Epidemiology 2900: Advanced Epidemiology of Aging

• Aging epidemiology 
• Diabetes complications in older adults 
• Neuromuscular and musculoskeletal function 
• Fall injuries and mobility 
• Medicare claims in epidemiologic studies 

Current and past research support

Principal Investigator

Current

• Bone microarchitecture and bone strength relationships to muscle quantity, quality and function in older adults: The Study of Muscle, Mobility and Aging (SOMMA). Co-PI: Cauley JA, 2019-2023, NIH/NIA
• Non-fracture fall injuries (NFFI) and long-term geriatric consequences in older women and men from a cross-cohort study, 2020-2024, NIH/NIA
• Clinical Characteristics, including History of MI and Stroke, among US Post-Menopausal Women Initiating Treatment with Romosozumab and Other Anti-Osteoporosis Therapies. Co-PI: McTigue KM, 2021-2025, Amgen Inc.
• T32 Training in the Epidemiology of Aging, 2021-2026, NIH/NIA

Past

• Individual and joint effects of the frailty phenotype, functional limitations and multimorbidity on health care costs and utilization, 2018-2019, NIH/NIA (Subcontract from University of Minnesota, PI: Ensrud KE)
• Peripheral nerve decline: an underappreciated cause of injurious falls, 2013-2017, NIH/NIA
• Sleep disordered breathing and sleep architecture in obesity and type 2 diabetes, 2012-2014, subcontract NIH/NHLBI (Subcontract from Temple University)
• Developmental Epidemiologic Cohort Study (DECOS) – Leg power sub-study, 2009-2011, NIH/NIA Laboratory of Epidemiology, Demography, and Biometry
• Peripheral nerve function decline in an aged cohort, 2007-2013, NIH/NIA 
• Longitudinal changes in bone mineral density with diabetes mellitus, 2005-2007, American Diabetes Association
• Epidemiology of bone mineral density in type 1 diabetic women and non-diabetic control women, 2001-2002, Lilly Center for Women’s Health

Co-Investigator

Current

• Diabetes Prevention Program Outcomes Study (DPPOS) - Phase 3 (PI, Pittsburgh site: Vendetti BM)
• The Study of Women's Health Across the Nation (SWAN): The Impact of Midlife and the Menopause Transition on Health and Functioning in Early Old Age, 2020-2024, NIH/NIA (PI, Coordinating Center:  Brooks M)
• Study of Muscle, Mobility and Aging (SOMMA), 2018-2023, NIH/NIA (PI: Newman AB)

Past

• Osteoporotic Fractures in Men Study (MrOS), 2013-2022, NIH/NIAMS (PI: Cauley JA)
• T32 Training in the Epidemiology of Aging, 2011-2022, NIH/NIA (PI: Newman AB)
• Study of Women's Health Across the Nation (SWAN) V: Coordinating Center, 2014-2019, NIH/NIA (PI: Brooks M)
• Exceptional survival: Trajectories to functional aging (CHS All Starts), 2011-2018, NIH/NIA (PI: Newman AB)
• Resilience to mobility impairment: neural correlates, 2011-2017, NIH/NIA (PI: Rosano C)
• Mobility and Independent Living in the Elderly Study (LIFE), 2009-2015, NIH/NIA (PI: Newman AB, subcontract from the University of Florida)
• Imaging biomarkers of accelerated brain aging in Type 1 Diabetes, 2010-2014, NIH/ NIDDK (PI: Rosano C)
• Epidemiology of diabetes complications (EDC) Phase II, 2009-2014, NIH/NIDDK (PI: Orchard TJ)
• Impact of Medicare Part D on racial disparities in diabetes, 2009-2012, AHRQ (PI: Donohue JM)
• Racial disparities in older adults: Impact of Medicare Part D, 2009-2012, NIH/NIA (PI: Hanlon JT)
• Exceptional aging: 12 year trajectories to function, 2004-2010, NIH/NIA (PI: Newman AB)

Consultant

Past

• Implementation of a sustainable active lifestyle intervention within the public health care sector framework, 2014-2015, Odense Municipality, Denmark (PI: Caserotti P)
• HANC 104-1.5-11, Implementation of an "Active Life-style" Intervention in Older People With Low Physical Function: Effect on Functional Impairments Pilot, 2013-2014, INTERREG 4A, European Regional Development Fund, European Union (PI: Caserotti P)

2021
Fellow, The American Society for Bone and Mineral Research (ASBMR)

2018-20
Chair, Health Sciences Section, Gerontological Society of America (GSA) 

2014
Fellow, The Gerontological Society of America (GSA) Health Sciences Section

2012
Department of Epidemiology Nominee for GSPH, University of Pittsburgh, ASPH/Pfizer Young Investigator’s Award for Distinguished Research in Public Health

2007
Health Sciences Research Award, Gerontological Society of America

2007
Endocrine Society and Pfizer, Inc. International Award for Excellence in The Journal of Clinical Endocrinology & Metabolism in 2006

2006
Alumni Award for 2005, University of Pittsburgh Postdoctoral Association (UPPDA)

2005
Summer Institute on Aging Research, National Institute on Aging

2001
Delta Omega Honor Society, Omicron Chapter, University of Pittsburgh, Graduate School of Public Health

1998
Delta Omega Award for best Epidemiology masters thesis, University of Pittsburgh, Graduate School of Public Health

1995
Graduate School of Public Health Scholarship, University of Pittsburgh

1995
Magna cum laude with high honors in English literature, Colgate University

1995
Phi Beta Kappa, National Honor Society, Colgate University

2006-present
Gerontological Society of America

2001-present
American Society for Bone and Mineral Research 

2001-present
American Diabetes Association

http://orcid.org/0000-0002-4093-6036

Highlights of major research areas and recent publications. A complete list of published work is included in My Bibliography: http://www.ncbi.nlm.nih.gov/pubmed/?term=Strotmeyer+ES

Chapters
Strotmeyer ES, Ward RE. Target populations, recruitment, retention, and optimal testing methods: Methodological issues for studies in the epidemiology of aging. In The Epidemiology of Aging. (Ed. Newman AB and Cauley JA). 2012. 

Vinik AI, Strotmeyer ES. Diabetic Neuropathy. In Pathy’s Principles and Practice of Geriatric Medicine, Fifth Edition (Ed. Sinclair AJ, Morley JE, and Vellas B). 2012. 

Strotmeyer ES, Cauley JA. Epidemiology of osteoporosis and fractures. In Atlas of Osteoporosis, Third Edition (Ed. Orwoll E). 2009. 

Review articles (*senior author manuscripts)

Karvonen-Gutierrez CA, Strotmeyer ES*. The urgent need for disability studies among mid-life adults. Women’s Midlife Health. 2020. Aug 28;6:8. doi: 10.1186/s40695-020-00057-w. eCollection 2020. PMID: 32864148

Ward RE, Caserotti P, Cauley JA, Boudreau RM, Goodpaster BH, Vinik AI, Newman AB, Strotmeyer ES*. Mobility-related consequences of reduced lower-extremity peripheral nerve function with age: A systematic review. Aging Dis. 2016 Aug;7(4):466-78. PMID:27493833 | PMCID:PMC4963190

Strotmeyer ES, Zgibor JC. Diabetes and Aging. Clin Geriatr Med. Clin Geriatr Med. 2015 Feb;31(1):xiii-xvi. PMID: 25453308 

Strollo S, Caserotti P, Ward RE, Glynn NW, Goodpaster BH, Strotmeyer ES.* A review of the relationship between leg power and selected chronic disease in older adults. Review. J Nutr Health Aging. 2015 Feb;19(2):240-8. PMID: 25651453 PMCID:PMC4840887

Vinik AI, Strotmeyer ES, Nakave AA, Patel CV. Diabetic neuropathy in older adults. Clin Geriatr Med. 2008 Aug;24(3):407-435, v review. PMID: 18672180 PMCID: PMC2706706 
 

Strotmeyer ES, Cauley JA. Diabetes mellitus, bone mineral density, and fracture risk. Curr Opin Endocrinol Diabetes Obes. 2007. 14:429-435. PMID: 17982347

Refereed articles (*senior author manuscripts), by topic area of expertise

Diabetes and neuromuscular impairments impact bone

Strotmeyer ES, Cauley JA, Schwartz AV, Nevitt MC, Resnick HE, Bauer DC, Tylavsky FA, de Rekeneire N, Harris TB, Newman AB. Nontraumatic fracture risk with diabetes mellitus and impaired fasting glucose in older white and black adults: the Health, Aging, and Body Composition Study. Arch Intern Med. 2005;25;165(14):1612-7.

Strotmeyer ES, Cauley JA, Schwartz AV, de Rekeneire N, Resnick HE, Zmuda JM, Shorr RI, Tylavsky FA, Vinik AI, Harris TB, Newman AB; Health ABC Study. Reduced peripheral nerve function is related to lower hip BMD and calcaneal QUS in older white and black adults: the Health, Aging and Body Composition Study. J Bone Miner Res. 2006;21(11):1803-10.

Strotmeyer ES, Kamineni A, Cauley JA, Robbins JA, Fried LF, Siscovick DS, Harris TB, Newman AB; the Cardiovascular Health Study. Potential explanatory factors for higher incident hip fracture risk in older diabetic adults. Curr Gerontol Geriatr Res. 2011;2011:979270. PMCID:PMC3152969

Schwartz AV, Vittinghoff E, Bauer DC, Hillier TA, Strotmeyer ES, Ensrud KE, Donaldson MG, Cauley JA, Harris TB, Koster A, Womack CR, Palermo L, Black DM; Study of Osteoporotic Fractures (SOF) Research Group; Osteoporotic Fractures in Men (MrOS) Research Group; Health, Aging, and Body Composition (Health ABC) Research Group. Association of BMD and FRAX score with risk of fracture in older adults with type 2 diabetes. JAMA. 2011;305(21):2184-92. PMCID:PMC3287389

Napoli N, Schwartz AV, Schafer AL, Vittinghoff E, Cawthon P, Parimi N, Orwoll E, Strotmeyer ES, Hoffman AR, Barrett-Connor E, Black DM; Osteoporotic Fractures in Men (MrOS) Study Research Group. Vertebral fracture risk in diabetic elderly men: The MrOS Study. J Bone Miner Res. 2018 Jan;33(1):63-69. PMID:28861910

Napoli N, Conte C, Pedone C, Strotmeyer ES, Barbour KE, Black DM, Samelson EJ, Schwartz AV. Effect of insulin resistance on BMD and fracture risk in older adults. J Clin Endocrinol Metab. 2019 Feb 25. pii: jc.2018-02539. doi: 10.1210/jc.2018-02539. [Epub ahead of print]. PMID: 30802282

Napoli N, Conte C, Eastell R, Ewing SK, Bauer DC, Strotmeyer ES, Black DM, Samelson EJ, Vittinghoff E, Schwartz AV. Bone turnover markers do not predict fracture risk in type 2 diabetes. J Bone Miner Res. 2020 Jul 27. doi: 10.1002/jbmr.4140. Epub 2020 Sep 29. PMID: 32717111

Neuromuscular and musculoskeletal impairments associated with physical performance and fall injuries

Strotmeyer ES, de Rekeneire N, Schwartz AV, Faulkner KA, Resnick HE, Goodpaster BH, Shorr RI, Vinik AI, Harris TB, Newman AB. The relationship of reduced peripheral nerve function and diabetes with physical performance in older white and black adults: the Health, Aging and Body Composition (Health ABC) Study. Diabetes Care. 2008 Sep;31(9):1767-72. PMCID:PMC2518342

Strotmeyer ES, de Rekeneire N, Schwartz AV, Resnick HE, Goodpaster BH, Faulkner KA, Shorr RI, Vinik AI, Harris TB, Newman AB; Health ABC Study. Sensory and motor peripheral nerve function and lower-extremity quadriceps strength: the Health, Aging and Body Composition Study. J Am Geriatr Soc. 2009 Nov;57(11):2004-10. PMCID:PMC2899705

Ward  RE, Boudreau RM, Caserotti P, Harris TB, Zivkovic S, Goodpaster BH, Satterfield S, Kritchevsky S, Schwartz AV, Vinik AI, Cauley JA, Newman AB, Strotmeyer ES*; for the Health ABC study. Sensory and motor peripheral nerve function and longitudinal changes in quadriceps strength. J Gerontol A Biol Sci Med Sci. 2015 Apr;70(4):464-70. PMCID:PMC4375416

Cawthon PM, Orwoll ES, Peter KE, Ensrud KE, Cauley JA, Kado DM, Stefanick ML, Shikany JM, Strotmeyer ES, Glynn NW, Caserotti P, Shankaran M, Hellerstein M, Cummings SR, Evans WJ. Strong relation between muscle mass determined by D3 creatine dilution, physical performance and incidence of falls and mobility limitations in a prospective cohort of older men. J Gerontol A Biol Sci Med Sci. 2019 May 16;74(6):844-852. doi: 10.1093/gerona/gly129. PMID: 29897420 PMCID: PMC6521914

Barbour KE, Sagawa N, Boudreau RM, Winger ME, Cauley JA, Nevitt MC, Fujii, Patel KV, Strotmeyer ES*. Knee osteoarthritis and the risk of medically treated injurious falls among older adults: the Health ABC Study. Arthritis Care Res (Hoboken). 2018 Aug 21. PMID:30133173 | PMCID: PMC6384154

Winger ME, Caserotti P, Cauley JA, Boudreau RM, Piva SR, Cawthon PM, Harris TB, Barrett-Connor E, Fink HA, Kado DM, Strotmeyer ES*. Associations between novel jump test measures, grip strength, and physical performance: the Osteoporotic Fractures in Men (MrOS) Study. Aging Clin Exp Res. 2020 Apr;32(4):587-595. DOI:   10.1007/s40520-019-01421-1  

Winger ME, Caserotti P, Ward RE, Boudreau RM, Hvid LG, Cauley JA, Piva SR, Harris TB, Glynn NW, Strotmeyer ES*. Jump power, leg press power, leg strength and grip strength differentially associated with physical performance: The Developmental Epidemiologic Cohort Study (DECOS). Exp Gerontol. 2021 Mar;145:111172. doi: 10.1016/j.exger.2020.111172. Epub 2020 Nov 24. PMID: 33245997

Vaarst J, Boyle E, Vestergaard S, Hvid LG, Strotmeyer ES, Glynn NW, Caserotti P. Does physical performance and muscle strength predict future personal and nursing care services in community-dwelling older adults aged 75+? Scand J Public Health. 2021 Jun;49(4):441-448. doi: 10.1177/1403494820979094. Epub 2021 Jan 19. PMID: 33467973

Xue L, Boudreau RM, Donohue JM, Zgibor JC, Marcum ZA, Costacou T, Newman AB, Waters TM, Strotmeyer ES*.  Persistent polypharmacy and fall injury risk: the Health, Aging and Body Composition Study. BMC Geriatrics. 2021 Dec 15;21(1):710. doi: 10.1186/s12877-021-02695-9. PMID: 34911467

Harris R, Strotmeyer ES, Sharma L, Kwoh CK, Brach JS, Boudreau R, Cauley JA. The association between severity of radiographic knee OA and recurrent falls in middle aged and older adults: The Osteoarthritis Initiative. J Gerontol A Biol Sci Med Sci. 2022 Feb 20:glac050. doi: 10.1093/gerona/glac050. Epub ahead of print. PMID: 35184161

Harris RJ, Parimi N, Cawthon PM, Strotmeyer ES, Boudreau RM, Brach JS, Kwoh CK, Cauley JA. Associations of components of sarcopenia with risk of fracture in the Osteoporotic Fractures in Men (MrOS) study. Osteoporos Int. 2022 Apr 5. doi: 10.1007/s00198-022-06390-2. Epub ahead of print. PMID: 35380213

Winger ME, Caserotti P, Cauley JA, Boudreau RM, Piva SR, Cawthon PM, Orwoll ES, Ensrud KE, Kado DM, Strotmeyer ES*; Osteoporotic Fractures in Men (MrOS) Research Group. Lower leg power and grip strength are associated with increased fall injury risk in older men: the Osteoporotic Fractures in Men (MrOS) Study. J Gerontol A Biol Sci Med Sci. 2022 Jun 5:glac122. doi: 10.1093/gerona/glac122. Epub ahead of print. PMID: 35662329

Diabetes, related metabolic factors, and complications, predict fall injuries and disability

Ward RE, Boudreau RM, Caserotti P, Harris TB, Zivkovic S, Goodpaster BH, Satterfield S, Kritchevsky SB, Schwartz AV, Vinik AI, Cauley JA, Simonsick EM, Newman AB, Strotmeyer ES*; Health, Aging and Body Composition Study. Sensory and motor peripheral nerve function and incident disability. J Am Geriatr Soc. 2014;62(12):2273-9. PMCID:PMC4270855

Lange-Maia BS, Newman AB, Cauley JA, Jakicic JM, Boudreau RM, Caserotti P, Glynn NW, Harris TB, Kritchevsky SB, Schwartz AV, Satterfield S, Simonsick EM, Vinik AI, Zivkovic S, Strotmeyer ES*. Sensorimotor peripheral nerve function and the longitudinal relationship with endurance walking in the Health, Aging and Body Composition Study. Arch Phys Med Rehabil. 2016;97(1):45-52. PMCID:PMC4696894

Espeland MA, Lipska K, Miller ME, Rushing J, Cohen RA, Verghese J, McDermott MM, King AC, Strotmeyer ES, Blair SN, Pahor M, Reid K, Demons J, Kritchevsky SB; LIFE Study Investigators. Effects of physical activity intervention on physical and cognitive function in sedentary adults with and without diabetes. J Gerontol A Biol Sci Med Sci. 2017 Jun 1;72(6):861-866. PMID:27590629

Botoseneanu A, Chen H, Ambrosius WT, Allore HG, Anton S, Chuch T, Folta SC, King AC, Nicklas BJ, Spring B, Strotmeyer ES, Gill TM. Effect of metabolic syndrome on the mobility benefit of a structured physical activity intervention. J Am Geriatr Soc. 2017 Jun;65(6):1244-1250. PMID:28369670 | PMCID:PMC5478451

Sagawa N, Marcum ZA, Boudreau RM, Hanlon JT, Albert SM, O’Hare C, Satterfield S, Schwartz AV, Vinik AI, Cauley JA, Harris TB, Newman AB, Strotmeyer ES*. Low blood pressure levels for fall injuries in older adults: the Health, Aging and Body Composition Study. Eur J Ageing. 2018.

Brown JD, Smith SM, Strotmeyer ES, Kritchevsky SB, Gill TM, Blair SN, Fielding RA, Buford TW, Pahor M, Manini TM. Comparative effects of ACE inhibitors and ARBs on response to a physical activity intervention in older adults: results from Lifestyle Interventions for Elders (LIFE) study. J Gerontol A Biol Sci Med Sci. 2019 May 9. pii: glz120. doi: 10.1093/gerona/glz120. [Epub ahead of print]. PMID: 31070702

Ylitalo KR, Strotmeyer ES, Pettee Gabriel K, Lange-Maia BS, Avis NE, Karvonen-Gutierrez CA. Peripheral nerve impairment and recurrent falls among women: Results from the Study of Women's Health Across the Nation. J Gerontol A Biol Sci Med Sci. 2019;Sep 24; pii: glz211. doi: 10.1093/gerona/glz211.

Lange-Maia BS, Karvonen-Gutierrez CA, Kazlauskaite R, Strotmeyer ES, Karavolos K, Appelhans BM, Janssen I, Avery EF, Dugan SA, Kravitz HM. Impact of chronic medical condition development on longitudinal physical function from mid- to early late-life: The Study of Women's Health Across the Nation. J Gerontol A Biol Sci Med Sci. 2019 Nov 16. pii: glz243. doi: 10.1093/gerona/glz243. [Epub ahead of print]. PMID: 31732730

Botoseneanu A, Chen H, Ambrosius WT, Allore HG, Anton S, Folta SC, King AC, Nicklas BJ, Spring B, Strotmeyer ES, Gill TM. Metabolic syndrome and the benefit of a physical activity intervention on lower-extremity function: Results from a randomized clinical trial. Exp Gerontol. 2021 Jul 15;150:111343. doi: 10.1016/j.exger.2021.111343. Epub 2021 Apr 10. PMID: 33848565

Napoleone JM, Boudreau RM, Lange-Maia BS, El Khoudary SR, Ylitalo KR, Kriska AM, Karvonen-Gutierrez CA, Strotmeyer ES*. Metabolic syndrome trajectories and objective physical performance in mid-to-early late life: The Study of Women’s Health Across the Nation (SWAN). J Gerontol A Biol Sci Med Sci. 2021 Jul 3;glab188. doi: 10.1093/gerona/glab188.

Methods and risk factor relationships with neuromuscular function in old age

Ward RE, Caserotti P, Faulkner K, Boudreau RM, Zivkovic S, Lee C, Goodpaster BH, Cawthon PM, Newman AB, Cauley JA, Strotmeyer ES*. Peripheral nerve function in lower extremity muscle power in older men. Arch Phys Med Rehabil. 2014;95(4):726-33. PMCID:PMC3972273

Lange-Maia BS, Cauley JA, Newman AB, Boudreau RM, Jakicic JM, Glynn NW, Zivkovic S, Dam T, Caserotti P, Cawthon PM, Orwoll ES, Strotmeyer ES*. Sensorimotor peripheral nerve function and physical activity in older men. J Aging Phys Act. 2016;24(4):559-566. PMCID:PMC5333760

Lange-Maia BS, Newman AB, Jakicic JM, Cauley JA, Boudreau RM, Schwartz AV, Simonsick EM, Satterfield S, Vinik AI, Zivkovic S, Harris TB, Strotmeyer ES*. Relationship between sensorimotor peripheral nerve function and indicators of cardiovascular autonomic function in older adults from the Health, Aging and Body Composition Study. Exp Gerontol. 2017 Oct 1;96:38-45. PMID:28442382 | PMCID: PMC5564447

Sparto PJ, Newman AB, Simonsick EM, Caserotti P, Strotmeyer ES, Kritchevsky SB, Yaffe K, Rosano C; Health ABC Study. Contributions to lateral balance control in ambulatory older adults. Aging Clin Exp Res. 2018 Jun;30(6):633-641. PMID:28836178 | PMCID:PMC5893439

Strotmeyer ES, Winger ME, Cauley JA, Boudreau RM, Cusick D, Collin RF, Chalhoub D, Buehring B, Orwoll E, Harris TB, Caserotti P. Normative values of muscle power using force plate jump tests in men aged 77-101 years: The Osteoporotic Fractures in Men (MrOS) Study. 2018;22(10):1167-1175.  doi: 10.1007/s12603-018-1081-x. 

Moorthi RN, Doshi S, Fried LF, Moe SM, Sarnak MJ, Satterfield S, Schwartz AV, Shlipak M, Lange-Maia BS, Harris TB, Strotmeyer ES*. Chronic Kidney Disease (CKD) and peripheral nerve function in the Health, Aging and Body Composition (Health ABC) Study. Nephrol Dial Transplant. 2019 Apr 1;34(4):625-632. PMID: 29757410 PMCID: PMC6452189

Lange-Maia BS, Karvonen-Gutierrez C, Strotmeyer ES, Avery EF, Appelhans BM, Fitzpatrick SL, Janssen Imke, Dugan SA, Kravitz HM. Factors influencing longitudinal stair climb performance from midlife to early late life: The Study of Women’s Health Across the Nation Chicago and Michigan Sites. J Nutr Health Aging. 2019;23(9):821-828. doi: 10.1007/s12603-019-1254-2.

Rech RS, Strotmeyer ES, Lange-Maia BS, Hugo FN, de Goulart BNG, Hilgert JB, Simonsick EM. Swallowing impairment in older adults: association with sensorimotor peripheral nerve function from the Health, Aging and Body Composition study. Aging Clin Exp Res. 2020 Apr 10. doi: 10.1007/s40520-020-01522-2. [Epub ahead of print]. PMID: 32277432

van der Velde JHPM, Koster A, Strotmeyer ES, Mess WH, Hilkman D, Reulen JPH, Stehouwer CDA, Henry RMA, Schram MT, van der Kallen CJH, Schalkwijk CG, Savelberg HHCM, Schaper NC. Cardiometabolic risk factors as determinants of peripheral nerve function: the Maastricht Study. Diabetologia. 2020 Jun 15. doi: 10.1007/s00125-020-05194-5. [Epub ahead of print]. PMID: 32537727

Doshi S, Moorthi RN, Fried LF, Sarnak MJ, Satterfield S, Shlipak M, Lange-Maia BS, Newman AB, Strotmeyer ES*. Chronic kidney disease as a risk factor for peripheral nerve impairment in older adults: A longitudinal analysis of Health, Aging and Body Composition (Health ABC) study. PLoS One. 2020 Dec 15;15(12):e0242406. doi: 10.1371/journal.pone.0242406. eCollection 2020. PMID: 33320861

Brenowitz WD, Robbins NM, Strotmeyer ES, Yaffe K. Associations of lower extremity peripheral nerve impairment and risk of dementia in Black and White older adults. Neurology. 2022 May 3;98(18):e1837-e1845. doi: 10.1212/WNL.0000000000200185. Epub 2022 Mar 9. PMID: 35264428; PMCID: PMC9109146

Study design and measurement in older populations, as relevant to functional ability  

Strotmeyer ES, Arnold AM, Boudreau RM, Ives DG, Cushman M, Robbins JA,  Harris TB, Newman AB. Long-term retention of older adults in the Cardiovascular Health Study: implications for studies of the oldest old. J Am Geriatr Soc. 2010 Apr;58(4):696-701. PMCID:PMC2903735

Lange-Maia BS, Newman AB, Strotmeyer ES, Harris TB, Caserotti P, Glynn NW. Performance on fast- and usual-paced 400-m walk tests in older adults: are they comparable? Aging Clin Exp Res. 2015 Jun;27(3):309-14. PMID:25373610 | PMCID:PMC4422783

Santanasto AJ , Coen PM, Glynn NW, Conley KE, Jubrias SA, Amati F, Strotmeyer ES, Boudreau RM, Goodpaster BH, Newman AB. The relationship between mitochondrial function and walking performance in older adults with a wide range of physical function. Exp Gerontol. 2016 Aug;81:1-7. PMID:27084585 | PMCID:PMC5483943

Duan-Porter, Vo TN, Ullman K, Langsetmo L, Strotmeyer ES, Taylor BC, Santanasto AJ, Cawthon PM, Newman AB, Simonsick EM, Waters TM, Ensrud KE. Hospitalization-associated change in gait speed and risk of functional limitations for older adults. J Gerontol A Biol Sci Med Sci. 2019 Feb 4. doi: 10.1093/gerona/glz027. PMID: 30715162

Sternfeld B, Colvin A, Stewart A, Appelhans BM, Cauley JA, Dugan SA, El Khoudary SR, Greendale GA, Strotmeyer E, Karvonen-Gutierrez C. Understanding racial/ethnic disparities in physical performance in mid-life women: Findings from SWAN (Study of Women's Health Across the Nation). J Gerontol B Psychol Sci Soc Sci. 2019 Aug 14. pii: gbz103. doi: 10.1093/geronb/gbz103. PMID: 31412129

Kline CE, Colvin AB, Pettee Gabriel K, Karvonen-Gutierrez CA, Cauley JA, Hall MH, Matthews KA, Ruppert KM, Neal-Perry GS, Strotmeyer ES, Sternfeld B. Associations between longitudinal trajectories of insomnia symptoms and sleep duration with objective physical function in postmenopausal women: the Study of Women's Health Across the Nation. Sleep. 2021 Mar 11:zsab059. doi: 10.1093/sleep/zsab059. Online ahead of print. PMID: 33705558

Moffit RE, Qiao Y, Moored KD, Santanasto AJ, Lange-Maia BS, Cawthon PM, Goodpaster BH, Strotmeyer ES, Newman AB, Glynn NW. Estimating cardiorespiratory fitness in older adults using a usual-paced 400-m long-distance corridor walk.  J Am Geriatr Soc. 2021;1-3. https://doi.org/10.1111/jgs.17360

Physical activity and lifestyle intervention associated with function, mobility and falls in older adults

Gill TM, Pahor M, Guralnik JM, McDermott MM, King AC, Buford TW, Strotmeyer ES, Nelson ME, Sink KM, Demons JL, Kashaf  SS, Walkup MP, Miller ME, the LIFE Study Investigators. Effect of structured physical activity on prevention of serious fall injuries in adults aged 70-89: randomized clinical trial (LIFE Study). BMJ. 2016 Feb 3;352:i245. PMCID:PMC4772786

Pettee Gabriel K, Sternfeld B, Colvin A, Stewart A, Strotmeyer ES, Cauley JA, Dugan S, Karvonen-Gutierrez. Physical activity trajectories during mid-life and subsequent risk of physical functioning decline in late mid-life: the Study of Women's Health Across the Nation (SWAN). Prev Med. 2017 Dec; 105:287-294. PMID:28987336 | PMCID:PMC5873953

Santanasto AJ, Glynn NW, Lovato L, Blair SN, Fielding RA, Gill TM, Guralnik JM, King A, Strotmeyer ES, Manini T, March AP, McDermott MM, Goodpaster BH, Pahor M, Newman AB. Effect of physical activity versus health education on physical function, grip strength and mobility: The LIFE Study. J Am Geriatr Soc. 2017 Jul;65(7):1427-1433. PMID:28221668 | PMCID:PMC5507738

Shechter A, Foster GD, Lang W, Reboussin DM, St-Onge MP, Zammit G, Newman AB, Millman RP, Wadden TA, Jakici JM, Strotmeyer ES, Wing RR, Pi-Sunyer FX, Kuna ST. Effects of a lifestyle intervention on REM sleep-related OSA severity in obese individuals with type 2 diabetes. J Sleep Res. 2017 Dec;26(6):747-755. PMID:28560832 | PMCID:PMC5705337

Kuna ST, Reboussin DM, Strotmeyer ES, Millman RP, Zammit G, Walkup MP, Wadden TA, Wing RR, Pi-Sunyer FX, Spira AP, Foster GD; Sleep AHEAD Research Subgroup of the Look AHEAD Research Group. Effects of weight loss on obstructive sleep apnea severity: 10-year results of the Sleep AHEAD study. Amer J Respir Crit Care Med 2021 Jan 15;203(2):221-229. doi: 10.1164/rccm.201912-2511OC. PMID: 32721163

Napoleone JE, Miller R, Devaraj S, Rockette-Wagner B, Arena V, Venditti E, Kramer K, Strotmeyer ES, Kriska AM. Impact of maintenance session attendance and early weight loss goal achievement on weight loss success in a community Diabetes Prevention Program-based intervention. Sci Diabetes Self Manag Care. 2021 Aug;47(4):279-289. doi: 10.1177/26350106211023990. Epub 2021 Jun 25. PMID: 34167389