Eleanor Feingold, PhD

I am a statistical geneticist. I develop statistical methods for questions in genetics, particularly involving genomic data and new technologies. I like digging into the gory details and understanding how data from new technologies need to be cleaned before they can be used. I also enjoy working with large collaborative groups to dissect the genetics of particular traits.  My current projects include:

• Detecting identity-by-descent and testing relationships using dense (sequence or chip) data
• Statistical properties of genome scan statistics
• Genetic epidemiology of Down syndrome and heart defects
• Genetics of meiotic recombination

• Genetic epidemiology of Alzheimer's disease
• Genetic epidemiology of dental and craniofacial traits

1985 | Massachusetts Institute of Technology | BS
1993 | Stanford University | PhD in Statistics

In Spring 2020 I will be teaching Risk Analysis in Genetic Counseling. I have also recently taught Introduction to Gene Mapping and Public Health Communications.

Here are a few of my most interesting recent publications (from over 150). See more on ORCID.

Zeng Z, Weeks DE, Chen W, Mukhopadhyay N, Feingold E. A Pipeline for Classifying Relationships Using Dense SNP/SNV Data and Putative Pedigree Information.Genetic Epidemiology. 2016 Feb; 40 (2):161-71. PMID: 26709242. doi:10.1002/gepi.21948.

Begum F, Sharker MH, Sherman SL, Tseng GC, Feingold E. Regionally Smoothed Meta-Analysis Methods for GWAS Datasets. Genetic Epidemiology. 2016 Feb; 40 (2):154-60. PMCID: PMC4724289. PMID: 26707090. doi: 10.1002/gepi.21949.

Leslie EJ, Liu H, Carlson JC, Shaffer JR, Feingold E, Wehby G, Laurie CA, Jain D, Laurie CC, Doheny KF, McHenry T, Resick J, Sanchez C, Jacobs J, Emanuele B, Vieira AR, Neiswanger K, Standley J, Czeizel AE, Deleyiannis F, Christensen K, Munger RG, Lie RT, Wilcox A, Romitti PA, Field LL, Padilla CD, Cutiongco-de la Paz EM, Lidral AC, Valencia-Ramirez LC, Lopez-Palacio AM, Valencia DR, Arcos-Burgos M, Castilla EE, Mereb JC, Poletta FA, Orioli IM, Carvalho FM, Hecht JT, Blanton SH, Buxó CJ, Butali A, Mossey PA, Adeyemo WL, James O, Braimah RO, Aregbesola BS, Eshete MA, Deribew M, Koruyucu M, Seymen F, Ma L, de Salamanca JE, Weinberg SM, Moreno L, Cornell RA, Murray JC, Marazita ML. A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3. American Journal of Human Genetics. 2016 Apr 7; 98 (4):744-54. PMCID: PMC4833215. PMID: 27018472. doi: 10.1016/j.ajhg.2016.02.014.

Kamboh MI, Fan KH, Yan Q, Beer JC, Snitz BE, Wang X, Chang CH, Demirci FY, Feingold E, Ganguli M. Population-based genome-wide association study of cognitive decline in older adults free of dementia: identification of a novel locus for the attention domain. Neurobiol Aging. 2019 Mar 11. pii: S0197-4580(19)30074-0. doi: 10.1016/j.neurobiolaging.2019.02.024. PMID: 30954325

Shaffer JR, LeClair J, Carlson JC, Feingold E, Buxo CJ, Christensen K, Deleyiannis FWB, Field LL, Hecht JT, Moreno L, Orioli IM, Padilla C, Vieira AR, Wehby GL, Murray JC,Weinberg SM, Marazita ML, Leslie EJ. Association of low-frequency genetic variants in regulatory regions with nonsyndromic orofacial clefts. Am J Med Genet A. 2018 Dec 24. doi: 10.1002/ajmg.a.61002. PMID: 30582786