Ada O Youk, PhD

Associate Professor and Vice Chair of Education, Biostatistics

Associate Dean of Academic Affairs, Office of the Dean

Director, MS Programs, Biostatistics

Associate Professor, Clinical & Translational Science

Associate Professor, Epidemiology


A728 Crabtree Hall, Public Health, 130 DeSoto Street, Pittsburgh, PA 15261
R-znvy: nlbhx@cvgg.rqh
Primary Phone: 967-179-0906

Personal Statement

I am an Associate Professor in Biostatistics and Director of MS Programs in Biostatistics at the University of Pittsburgh.  I am also Senior Biostatistician in the Center for Health Equity Research and Promotion (CHERP) Biostatistics and Informatics Core at the VA Pittsburgh Healthcare System. In my roles as Principal Investigator, Co-Investigator, and Lead Biostatistician, I have primary responsibility for statistical integrity, including conceptualization, design, and grant development, recruitment/data collection, monitoring, analysis, reporting, and manuscript preparation. My primary area of statistical expertise is regression modeling with extensive experience analyzing big data from large administrative data systems as well as prospective clinical trials and epidemiological studies involving time to event modeling and mixed effects modeling. I have maintained successful research collaborations most recently with VA investigators. In my roles as Educator and Mentor, I teach courses in introductory biostatistics, applied regression analysis, scientific communication skills, mathematical methods for statistics, and mixed models as well as direct the MS Capstone in Biostatistics in Pitt Public Health. I have mentored over 100 students, fellows and early career faculty and 30% of my peer-reviewed publications are with mentees. 







Duquesne University

Pittsburgh, PA

B.A. (Cum Laude), 1988







University of Pittsburgh

Pittsburgh, PA

M.A., 1990

Applied Statistics


University of Pittsburgh

Pittsburgh, PA

Ph.D., 1996



BIOS 2011 Principles of Statistical Reasoning

BIOST 2041 Introduction to Statistical Methods

BIOS 2049 Applied Regression Analysis

BIOS 2058 Scientific Communications Skills

BIOS 2081 Mathematical Methods for Statistics

BIOS 2086 Applied Mixed Models

BIOS 2099 Biostatistics Capstone

PUBHLT 0310 Introduction to Public Health Biostatistics

Selected Publications

  1. Arya S, Varley P, YOUK A, Borrebach J, Perez S, Massarweh NN, Johanning JM, Hall DE.  Recalibration and External Validation of the Risk Analysis Index:  A Surgical Frailty Assessment. Annals of Surgery, 2020;272(6): 996-1005.
  1. Rogal S, YOUK A, Zhang H, Gellad WF, Fine MJ, Good CB, Chartier M, DiMartini A, Morgan T, Batalle R, Kraemer KL. Impact of Alcohol Use Disorder Treatment on Clinical Outcomes among Patients with Cirrhosis. Hepatology, 2020; 71(6):2080-2092.  doi: 10.1002/hep.31042.
  1. Shinall M, Arya S, YOUK AO, et al. Association of preoperative patient frailty and operative stress with postoperative mortality.  JAMA Surg. 2020;155(1):e194620. doi:10.1001/jamasurg.2019.4620.
  1. **Tighe CA, YOUK A, Ibrahim SA, Weiner DK, Vina ER, Kwoh CK, Gallagher RM, Bramoweth AD, Hausmann LRM. Pain Catastrophizing and Arthritis Self-Efficacy as Mediators of Sleep Disturbance and Osteoarthritis Symptom Severity.  Pain Medicine, 2020; 21(3):501-510. doi: 10.1093/pm/pnz187
  1. Folb BL, Klem ML, YOUK AO, Dahm JJ, He M, Ketchum AM, Wessel CB, Hartman LM. Continuing education for systematic reviews: a prospective longitudinal assessment of a workshop for librarians. J Med Libr Assoc, 2020; 108(1):36-46. doi: 10.5195/jmla.2020.492.
  1. Shah R, Borrebach JD, Hodges JC, Varley PR, Wisniewski MK, Shinall MC Jr, Arya S, Johnson J, Nelson JB, YOUK A, Massarweh NN, Johanning JM, Hall DE. Validation of the Risk Analysis Index for Evaluating Frailty in Ambulatory Patients. J Am Geriatr Soc. 2020; 68:1818‐1824. doi: 10.1111/jgs.16453.
  1. Shinall MC, YOUK A, Massarweh NN, Shireman PK, Arya S, George EL, Hall DE. Association of pre-operative frailty and operative stress with mortality after elective vs emergency surgery. JAMA Netw Open, 2020; 3(7):e2010358. doi:10.1001/jamanetworkopen.2020.10358
  1. **Frederick AN, Pardo AD, Schmiedt CW, Hinson WD, YOUK AO, Urie BK.  Outcomes for dogs with functional thyroid tumors treated by surgical excision alone. Journal of the American Veterinary Medical Association, 2020; 256(4):444-448.
  1. **Bramoweth AD, Lederer LG, YOUK AO, Germain A, Chinman MJ. Brief behavioral treatment for insomnia vs. cognitive behavioral therapy for insomnia: Results of a randomized non-inferiority clinical trial among veterans. Behavior Therapy, 2020; 51(4):535-547.
  1. McClendon J, Essien UR, YOUK A, Ibrahim SA, Vina E, Kwoh CK, Hausmann LRM. Cumulative Disadvantage and Disparities in Depression and Pain among Veterans with Osteoarthritis: The Role of Perceived Discrimination. Arthritis Care & Research, 2021; 73 (1), 11-17.
  1. George EL, Hall DE, YOUK A, Chen R, Kashikar A, Trickey AW, Varley PR, Shireman P, Shinall MC, Massarweh NN, Johanning J, Arya S.  Association between patient frailty and postoperative mortality across multiple noncardiac surgical specialties.  JAMA Surgery, 2021; 156(1):e205152.  doi:10.001/jamasurg.2020.5152
  1. *Paul P, Hammer A, Rositch AF, Burke AE, Viscidi RP, Silver MI, Campos M, YOUK AO, Gravitt PE. Rates of new human papillomavirus detection and loss of detection in middle-aged women by recent and past sexual behavior.  J Infect Dis. 2021; 223(8):1423-1432 doi: 10.1093/infdis/jiaa557.
  1. Boyer TL, YOUK AO, Haas AP, Brown GR, Shipherd JC, Kauth MR, Jasuja GK, Blosnich JR.  Suicide, homicide, and all-cause mortality among transgender and cisgender patients in the Veterans Health Administration.  LGBT Health, 2021; 8(3):173-180.
  1. Zupa MF, Piette JD, Stoll SC, Obrosky DS, Kelly MB, YOUK AO, Overholt L, Trivedi R, Heisler M, Rosland AM.  Patient and Supporter Factors Affecting Engagement with Diabetes Telehealth.  American Journal of Managed Care, 2021.  In press.
  2. Rogal S, YOUK A, Agbalajobi O, Zhang H, Gellad W, Fine MJ, Belperio P, Morgan T, Good CB, Kraemer K. Medication Treatment of Active Opioid Use Disorder in Veterans with Cirrhosis.  American Journal of Gastroenterology, 2021.  In press.
  1. *Bulas AM, Li Lihua, Kumar RG, Mazumdar M, Rosso AL, YOUK AO, Dams-O’Connor K. Pre-Injury Health Status of Adults with Traumatic Brain Injury: A Preliminary Matched Case-Control Study. The Journal of Head Trauma Rehabilitation. In press.
  1. Zupa MF, Lee AA, Piette JD, Trivedi R, YOUK AO, Heisler M, Rosland AM. Impact of a Family Support Intervention on Supporter Involvement in Helping Adults Manage Type 2 Diabetes. Journal of General Internal Medicine, 2021. In press.
  1. Yan Q, Kim J, Hall DE, Shinall MC Jr, Reitz KM, Stitzenberg KB, Kao LS, George EL, YOUK A, Wang CP, Silverstein JC, Bernstam EV, Shireman PK. Association of Frailty and the Expanded Operative Stress Score with Preoperative Acute Serious Conditions, Complications and Mortality in Males Compared to Females – A Retrospective Observational Study. Ann Surg, 2021. In press.
  1. Reitz KM, Varley PR, Liang NL, YOUK A, George EL, Shinall MC, Shireman PK, Arya S, Tzeng E, Hall DE. The Correlation Between Case Total Work Relative Value Unit, Operative Stress and Patient Frailty: Retrospective Cohort Study. Ann Surg, 2021.  In press.

*          co-authored with student

**  co-authored with fellow




Ada O Youk