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Biostatistics Seminars

Department of Biostatistics Seminar Series


The Department of Biostatistics presents a regular speaker series each semester, generally on Thursday afternoon each week. Diverse experts lecture on their work in biostatistics.

Upcoming Biostats Seminars

Biostatistics Seminar Series

Dynamic functional clustering with applications to the MAPP Study-Wensheng Guo-UPenn

Thursday 4/19 3:30PM - 4:30PM
Public Health Lecture Hall (A115)

Biostatistics guest speaker, Wensheng Guo, University of Pennsylvania, will present, "Dynamic functional clustering with applications to Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) study."

In this talk, I will present some works under development by our group on functional clustering and dimension reduction methods. The proposed methods are motivated by, and are applied to the data collected in the NIDDK-funded Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. This is a longitudinal cohort study that collects high dimensional longitudinal urological chronic pelvic pain syndrome (UCPPS) symptom data together with many other biomarkers, neuroimaging data and genetic data. The goal of the study is to identify risk factors that can predict whether a subject would be worsening or improving and to understand the underlying pathological mechanisms. We first propose a dynamic functional clustering algorithm where each group of curves are modeled by a functional mixed effects model, and the posterior probability is used to iteratively classify each subject into different subgroups.  The functional mixed effects model allows flexible designs and nested structures. The classification takes into account both group-average trajectories and between-subject variability. We propose an equivalent dynamic state space model to calculate the likelihood in fitting the model, and to efficiently compute the posterior probability in classifying a new subject. The resultant sequential algorithm is O(n) and can be implemented online. We also propose a leave-one-subject-out cross-validation Kullback-Leibler information criterion to choose the number of clusters.  The performance is assessed through a simulation study, and we apply the proposed methods to longitudinal urological chronic pelvic pain syndrome symptom data collected in the MAPP Research  Network and identify three subgroups 

Last Updated On Wednesday, March 28, 2018 by Temp, GSPH Marketing & Development
Created On Friday, January 05, 2018

Previous Biostats Seminars

Thu 6/14/2018
Biostatistics Seminar: Jenna Carlson, University of Pittsburgh Biostatistics Seminar Series
Biostatistics Seminar: Jenna Carlson, University of Pittsburgh
Thu 6/14/2018 3:00PM - 4:00PM
1149 Public Health, Foster Conference Room

Biostatistics guest speaker, Jenna Carlson, University of Pittsburgh, will present, "Population-Specific Reference Panels and Genetic Association Studies in Sāmoans."
Tue 5/29/2018
Biostatistics Seminar: Zeda Li, City University of New York Biostatistics Seminar Series
Biostatistics Seminar: Zeda Li, City University of New York
Tue 5/29/2018 2:00PM - 3:00PM
1149 Public Health, Foster Conference Room

Zeda Li, Paul H. Chook Department of Information Systems and Statistics, City University of New York, will present, “Adaptive Bayesian Time-Frequency Analysis of Multivariate Time Series”.

Thu 4/19/2018
Dynamic functional clustering with applications to the MAPP Study-Wensheng Guo-UPenn Biostatistics Seminar Series
Dynamic functional clustering with applications to the MAPP Study-Wensheng Guo-UPenn
Thu 4/19/2018 3:30PM - 4:30PM
Public Health Lecture Hall (A115)

Biostatistics guest speaker, Wensheng Guo, University of Pennsylvania, will present, "Dynamic functional clustering with applications to Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) study."
Thu 4/12/2018
Biostatistical Methods for Wearable and Implantable Technology-Ciprian Crainiceanu-Johns Hopkins Biostatistics Seminar Series
Biostatistical Methods for Wearable and Implantable Technology-Ciprian Crainiceanu-Johns Hopkins
Thu 4/12/2018 3:30PM - 4:30PM
Public Health Auditorium (G23)

Biostatistics guest speaker, Ciprian Crainiceanu, Johns Hopkins University, will review some of the most used and useful sensors in Health Sciences and the ever expanding WIT (Wearable and Implantable Technology) analytic environment.

Thu 4/5/2018
A Logistic Regression Measurement Error Model For High-Dimensional Longitudinal Predictors Biostatistics Seminar Series
A Logistic Regression Measurement Error Model For High-Dimensional Longitudinal Predictors
Thu 4/5/2018 3:30PM - 4:30PM
Public Health Auditorium (G23)

Biostatistics guest speaker, Seonjoo Lee, Columbia University, will present, "A Logistic regression measurement error model for high-dimensional longitudinal predictors."
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Contact

For information on seminars and events in the department, contact:

Bernadette Kapko
bkapko@pitt.edu
412-624-3022

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