Meetings of the Eastern North American Region of the International Biometric Society (a.k.a. "ENAR meetings") are held in late March or early April each year and reflect the broad interests of the Society, including both quantitative techniques and application areas. Faculty and student presenters from the Department of Biostatistics regularly participate giving invited talks, contributed talks, and poster presentations.
The Joint Statistical Meetings, known simply as "JSM", is the largest gathering of statisticians held annually in North American. Faculty and student presenters from the Department of Biostatistics regularly participate giving invited talks, contributed talks, and poster presentations. Our students often receive top awards and participate in the affiliated career marketplace at the event.
Biostatistics guest speaker, David Gerard, University of Chicago, will present, " Better Genotyping for Polyploids."
Modern genomics has revolutionized how we answer questions about evolution, population dynamics, medicine, and plant and animal breeding. To answer these questions, we must first be able to detect and quantify (or "genotype") differences in individual genomes. Many scientists have used next generation sequencing technologies to genotype diploid individuals (those with two copies of their genomes). However, methods to genotype polyploids (those with morethan two copies of their genomes) are just emerging. We present two main contributions: (i) many datasets feature related individuals, and so we use the structure of Mendelian segregation to borrow strength between polyploid siblings to improve genotyping; (ii) we additionally draw attention to and then model common aspects of next generation sequencing data: sequencing error, allele bias, overdispersion, and outlying observations. We apply our method to a dataset of hexaploid sweet potatoes and discuss future extensions.
Last Updated On Friday, January 12, 2018 by Kapko, Bernadette E
Created On Friday, January 5, 2018
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