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Pitt Men’s Study contributes to aging and cognition finding

The demographics of the HIV epidemic in the U.S. shift toward older age, IDM’s Pitt Men’s Study contributed to an article in Lancet on neurocognition in older HIV patients. The longitudinal study, which included more than 5,000 participants enrolled in the Multicenter AIDS Cohort Study, found a greater-than-expected effect of aging on episodic memory and motor function with advanced stages of HIV infection. This suggests that these two domains are most susceptible to the progression of neurocognitive impairment caused by aging in people with HIV. The researchers, including JAMES T. BECKER, of the University of Pittsburgh Department of Psychiatry, concluded that older individuals with HIV infection should be targeted for regular screening for HIV-associate neurocognitive disorder, particularly with tests referable to the episodic memory and motor domains. 

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