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Mailliard on how cells talk and help one another via tiny tube networks

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SCIENTIFIC AMERICAN - Working with dendrites, what he calls "the quarterbacks of the immune system," IDM's ROBBIE MAILLIARD and colleagues are applying the budding field of TNT research to HIV. Now, they are investigating whether drugs that are commonly used to lower cholesterol levels could be repurposed to control viral infections.   

Dean's Day 2018 IDM departmental award recipients

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Department of Infectious Diseases and Microbiology awards during our annual Dean's Day student research competition were given to KELSEY MESSERSCHMIDT (MPH '19), BETHANY FLAGE (MS '18), ROBERTA METTUS (MS '19), and RENEE ANDERKO (PhD '22).  

2018 Celebration of Student Awards

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On April 28, 2018, Pitt Public Health celebrated recent graduates with awards given upon the culmination of a degree program. Delta Omega's honor society inductees were announced and outstanding thesis/essay and dissertation awards were conferred. Outstanding Student Awards were also given at both the master's and doctoral level, as well as Dean's Service Awards.  

Marques on new device that could lead to earlier detection of outbreaks

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NEW YORK TIMES - Researchers created a device that can test a drop of blood to tell, in about half an hour, who's immune to certain infections and who's not. The goal is to find groups of people at risk of outbreaks, especially in impoverished and remote areas, in time to save lives. "We need to develop cheaper and more efficient ways to detect outbreaks earlier," said IDM's ERNESTO MARQUES. “This may be one step in that direction.”  

Three MPH students selected for the Milken Institute's Health Leaders Program

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The Milken Institute is a nonprofit, nonpartisan think tank determined to increase global prosperity by advancing collaborative solutions that widen access to capital, create jobs, and improve health. In 2018, they launched the Future Health Leaders Pilot Program to create the right connections between organizations, students, and schools. Students chosen this year from Pitt Public Health are KAITLYN SAAL-RIDPATH (JD/MPH ’20), JESSICA SALERNO (I... 

Celebrate 70: Global health impact (video)

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Faculty and alumni spoke on a panel to highlight the public health impact on global communities, including immigration crises, planetary health, climate change, and the importance of health systems. KELLY SALDANA (BCHS ’01) talked about creating resiliency and figuring out what that means both at the individual level and the systems level to help lessen negative effects of climate change.  

Perkins invited back to present at IDM Seminar Series

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Douglas J. Perkins, a former assistant professor in IDM (2001-2007), was invited back to present at the IDM Seminar Series on March 28. His presentation was on "Genomic Approaches for Uncovering the Pathogenesis of Severe Malarial Anemia in African Children."  

Salerno selected for summer program in Colombia

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JESSICA SALERNO (IDM '20) has been selected to participate in Red Tree Study's Academic Summer Program at the Institute of Public Health at Pontificia Universidad Javeriana in Bogota, Colombia. In this program, students learn from experts while helping to ensure the health of Colombian citizens as the country transitions towards peace.   

Rappocciolo presents research on cell cholesterol dysregulation in HIV non-progressors at 2018 Conference on Retroviruses and Opportunistic Infections

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IDM's GIOVANNA RAPPOCCIOLO presented at the Conference on Retroviruses and Opportunistic Infections ion biomarkers and genetics of cell cholesterol dysregulation in HIV non-progressors. Co-authors include IDM faculty J MARTINSON and C RINALDO and recent doctoral graduate DIANA DELUCIA.   

Melody receives postdoctoral fellowship

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University of Texas Medical Branch-Galveston has offered KEVIN MELODY (IDM '17) a postdoctoral fellowship in a BSL-4 research group headed by Thomas Geisbert. Due to the security and proficiency needed to perform the work, Kevin will undergo extensive training before beginning high-containment pathogen-related research.  

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Recent IDM Publications

Rift Valley fever in animals and humans: Current perspectives 

Rift Valley fever in animals and humans: Current perspectives

ANTIVIRAL RESEARCH - McMillen and Hartman discuss the historical role of Rift Valley Fever (RVF) as a biological weapon and conclude with an outline of the important unanswered questions for ongoing research into this important zoonotic disease. (06/11/2018)

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN 

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN

JOURNAL OF VIROLOGY - Delucia, Rinaldo, Rappocciolo demonstrate that the use of SIMV to decrease macrophage-mediated virus transfer should be considered for future HIV therapeutic development.  (05/18/2018)

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury 

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury

JOURNAL OF NEUROINFLAMMATION - Guha, Wagner, Ayyavoo conduct first study evaluating the potential role of Ng in the context of HIV-1 neropathogens and conclude that synaptic damage in HAND+ patients could be a result of abrogation of Ng through HIV-1 induced inflammation that dysregulates Ng-CaM in... (05/18/2018)

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques 

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques

JOURNAL OF IMMUNOLOGY - Wonderlich, Swan, Bissel, Hartman, Carney, O'Malley, Obadan, Santos, Walker, Sturgeon, Frye, Maiello, Scanga, Bowling, Duangkhae, Wiley, Flynn, Wang, Cole, Reed, Barratt-Boyes establish a new nonhuman primate disease model for evaluation of vaccine and therapeutic approaches... (02/14/2018)

Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4+ T cells 

Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4+ T cells

NATURE MEDICINE - Gupta, Sanyal, Ratner, Ding, Zerbato, Giacobbi, Venkatachari, Patterson, Chargin, Chen, Mailliard, Rinaldo, and Sluis-Cremer found that the size of the inducible latent HIV-1 reservoir in aviremic subjects on ART is approximately 70-fold larger than previous estimates.  (02/08/2018)

Peripheral blood biomarkers of disease outcome in a monkey model of rift valley fever encephalitis.  

Peripheral blood biomarkers of disease outcome in a monkey model of rift valley fever encephalitis.

JOURNAL OF VIROLOGY - Wonderlich, Caroline, McMillen, Walters, Reed, Barratt-Boyes, and Hartman conclude that African green monkeys are a novel and suitable model for studying the neuropathogenesis of Rift Valley Fever (RVF) and for testing vaccines and therapeutics against this important emerging ... (02/05/2018)

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