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IDM Faculty News

Amid opioid crisis, Frank addresses Titusville community

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TITUSVILLE HERALD - Community members and students from Pitt's Titusville campus gathered to hear IDM's LINDA FRANK discuss drug misuse versus drug abuse, the opioid epidemic's relation to to the spread of HIV/AIDS and Hepatitis C, available prevention and treatment strategies, and the implications for health professionals, families, community members, and local organizations.   

As Zika babies become toddlers, some can’t see, walk, or talk

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NEW YORK TIMES - Infectious disease researcher ERNESTO MARQUES says about 3 percent of 1,000 pregnant Brazilian women in a recent sample were infected with Zika. “The problem’s not going away. We are still having cases. And the future of Zika babies already born is complicated by poverty and strained resources. “Most of these babies are from low socioeconomic status and rely on the public health system to provide care. It’s very difficult to mana... 

Mailliard presents research on improving HIV “kick and kill” strategies to IAS Conference on HIV Science in Paris (Video)

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YOUTUBE - IDM's Mailliard presents his research on “kick and kill” strategies at the 9th IAS Conference on HIV Science, the world's largest open scientific conference on HIV and AIDS-related issues. The work demonstrates that naïve T cells have the ability to effectively target the HIV-1 reservoir, highlighting the importance of directing HIV-1 curative strategies towards the induction of de novo rather than memory HIV-1-specific CTL responses.  

Stall’s research helps to “Kick ASS”

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SAN FRANCISCO BAY TIMES - The reality of AIDS Survivor Syndrome (ASS) is now being confirmed by empirical research. On November 3, 2017, BCHS Associate Chair for Science RON STALL presented his findings on the subject in San Francisco at a provider and community town hall entitled “Research on the AIDS Survivor Syndrome: New Data from The Multi-Center AIDS Cohort Study and Voices of Survivors Themselves.” 

Marques: While Zika hasn’t been in the news much, that doesn’t mean it’s gone

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WASHINGTON POST - Local transmission seems to have come to a standstill, with one suspected case in Texas and one case confirmed in Florida. Herd immunity may be preventing more big outbreaks. But if Zika behaves like other arboviruses, it will probably stick around. They tend to be cyclical, says Pitt Public Health researcher ERNESTO MARQUES. “You have big booms, then they drop. Then a few years later, they come back again.” 

Enigma: Marques worked to pinpoint culprit of mysterious illness in Brazil

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PITTWIRE - When a mysterious illness suddenly emerged in his Brazilian hometown, IDM researcher ERNESTO MARQUES mobilized with colleagues to decode its unknowns. The work may help infectious-disease researchers stop or stall new epidemics. His story begins on page 18. 

Frank on Telehealth Appalachian AIDS Education and Training (video)

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The Telehealth Appalachian AIDS Education and Training Center Project, led by IDM's LINDA FRANK, provides web-based HIV education, training, clinical guidelines, and resources to Appalachian community health centers. Frank has worked to increase knowledge and awareness about HIV disease in underserved communities in the hope of preventing discrimination and delivering more care to those who need it.  

Marques: Zika virus still offers no clear answers

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THE GLOBE AND MAIL - It has been two years since Brazil’s northeast was hit with the public-health crisis that left babies born with CZS and set off alarm bells in the global health community. Yet experts continue to grapple with big questions. “We can’t really tell if what happened here was replicated or not in other areas of Brazil or Latin America because we don’t really know how many women were exposed,” said IDM’s ERNESTO MARQUES, who is con... 

Frank addresses surgeon general report on opioid epidemic (video)

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WPXI - "We've got to increase public health awareness of addiction. A lot of people think, 'It's not my family, it's not me, it's not my community,' and we know that it can be anybody." IDM's LINDA FRANK talks to NIGHTTalk about opioid addiction in Pittsburgh and around the country.  

2017 faculty and staff Delta Omega initiates

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The following four individuals will be inducted into the Omicron chapter of the Delta Omega Honorary Society at the Graduate School of Public Health, recognizing merit and encouraging further excellence in, and devotion to, public health work: Nancy W. Glynn (EPI '94), faculty and alumna; Leah M. Lamonte (IDM '06), alumna; Natalie A. Solomon-Brimage (BCHS '06), alumna; Christopher A. Taylor (EPI '10), alumnus. 

Rotarian director talks with Salk and Burke about polio eradication (video)

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A round-table was held today with some amazing minds on the issue of polio eradication: Jennifer Jones, director of Rotary International; PETER SALK, IDM visiting professor and son of research pioneer Jonas Salk; and DONALD BURKE, school dean and University associate vice chancellor of global health. Rotary has been raising awareness that "We are this close to ending polio!" While all were in Pittsburgh, they shared amazing conversation about the... 

IDM's Peter Salk on importance of Julius Youngner, polio vaccine pioneer, dead at 96

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NEW YORK TIMES - “I think it’s absolutely fair to say that had it not been for Dr. Youngner, the polio vaccine would not have come into existence,” PETER SALK president of the Jonas Salk Legacy Foundation and a visiting professor at the University of Pittsburgh Graduate School of Public Health, said in an e-mail. He added, “The really important thing to recognize is that the development of the polio vaccine at the University of Pittsburgh was a t... 

Marques offers insignt as Zika season approaches

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TRIB LIVE - In the U.S., there have been 5,264 Zika cases reported, with the vast majority in travelers returning from affected areas in other countries, says ERNESTO MARQUES, associate professor with Pitt Public Health and scientific director of CURA ZIKA, an international alliance with counterparts in Brazil to help fundraising for research into the virus. Learn more about Cura Zika at www.publichealth.pitt.edu/curazika. 

Marques looks for clues to Zika damage in twins

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NEW YORK TIMES - Determining why one twin becomes infected in the womb while the other does not may illuminate how Zika crosses the placenta, how it enters the brain, and whether any genetic mutations make a fetus more resistant or susceptible to Zika infection. Perhaps the virus entered through a weak spot in one placenta’s membrane, said ERNESTO MARQUES, an infectious disease expert at Pitt Public Health and the Oswaldo Cruz Foundation in Recif... 

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Recent IDM Publications

Inefficient HIV-1 trans Infection of CD4+ T Cells by Macrophages from HIV-1 Nonprogressors Is Associated with Altered Membrane Cholesterol and DC-SIGN 

Inefficient HIV-1 trans Infection of CD4+ T Cells by Macrophages from HIV-1 Nonprogressors Is Associated with Altered Membrane Cholesterol and DC-SIGN

JOURNAL OF VIROLOGY - DeLucia, Rinaldo, and Rappocciolo show that efficiency of MΦ-mediated HIV trans infection of CD4+ T cells is a unique characteristic associated with control of disease progression, and it is impaired in HIV-infected NP. Their work demonstrates that the use of SIMV to decrease ... (06/27/2018)

Development of antibody biomarkers of long term and recent dengue virus infections 

Development of antibody biomarkers of long term and recent dengue virus infections

JOURNAL OF VIROLOGICAL METHODS - BURKE, MARQUES, and colleagues discuss anti-dengue NS1-specific IgG and IgG3 as potential biomarkers of long-term and recent (less than 6 months) DENV infections, respectively.  (06/14/2018)

Tradition and innovation in development of a Zika vaccine 

Tradition and innovation in development of a Zika vaccine

THE LANCET - MARQUES and BURKE comment about two Zika vaccines in clinical development and describe the challenges ahead. (06/14/2018)

Zika virus displacement by a chikungunya outbreak in Recife, Brazil 

Zika virus displacement by a chikungunya outbreak in Recife, Brazil

PUBLIC LIBRARY OF SCIENCE - Magalhaes, Braga, Cordeiro, Oliveira, Castanha, Maciel, Amancio, Gouveia, Peixoto-deSilva Jr., Peixoto, Britto, Lima, Lima, and Marques detected the tail end of a Zika epidemic in 2015-16 which was displaced by a chikungunya epidemic. Few dengue cases were identified des... (06/14/2018)

Rift Valley fever in animals and humans: Current perspectives 

Rift Valley fever in animals and humans: Current perspectives

ANTIVIRAL RESEARCH - McMillen and Hartman discuss the historical role of Rift Valley Fever (RVF) as a biological weapon and conclude with an outline of the important unanswered questions for ongoing research into this important zoonotic disease. (06/11/2018)

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN 

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN

JOURNAL OF VIROLOGY - Delucia, Rinaldo, Rappocciolo demonstrate that the use of SIMV to decrease macrophage-mediated virus transfer should be considered for future HIV therapeutic development.  (05/18/2018)

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury 

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury

JOURNAL OF NEUROINFLAMMATION - Guha, Wagner, Ayyavoo conduct first study evaluating the potential role of Ng in the context of HIV-1 neropathogens and conclude that synaptic damage in HAND+ patients could be a result of abrogation of Ng through HIV-1 induced inflammation that dysregulates Ng-CaM in... (05/18/2018)

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques 

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques

JOURNAL OF IMMUNOLOGY - Wonderlich, Swan, Bissel, Hartman, Carney, O'Malley, Obadan, Santos, Walker, Sturgeon, Frye, Maiello, Scanga, Bowling, Duangkhae, Wiley, Flynn, Wang, Cole, Reed, Barratt-Boyes establish a new nonhuman primate disease model for evaluation of vaccine and therapeutic approaches... (02/14/2018)
© 2018 by University of Pittsburgh Graduate School of Public Health

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