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Biostatistics Dissertation Defenses

Biostatistics Dissertations

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Events that appear on this page are in the Sponsoring Department of "Biostatistics" with "Dissertation Defenses" as its Category.

To add or edit events on this page, go to http://publichealth.pitt.edu/submit

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Biostatistics Dissertation Defense

Yongli Shuai: Multinomial Logistic Regression and Prediction Accuracy for Interval-Censored...

Friday 12/8 11:30AM - 1:30PM
Public Health 7139

Yongli Shuai of the Department of Biostatistics defends his dissertation on "Multinomial Logistic Regression and Prediction Accuracy for Interval-Censored Competing Risks Data".

Graduate faculty of the University and all other interested parties are invited to attend


ABSTRACT:

Interval-censored competing risks data are ubiquitous in biomedical research fields. The direct parametric modeling of the cumulative incidence functional (CIF) is appealing due to its intuitive probability interpretation and easy implementation. This dissertation is to study and extend the multinomial logistic regression (MLR) model to interval-censored competing risks data. The MLR model naturally guarantees the additivity property of the event-specific probabilities under competing risks. A cubic B-Spline-based sieve method is then adopted to add flexibility into the proposed MLR model. The second study objective is to develop the prediction error (PE) as a model-free metric to evaluate and validate the prediction accuracy for interval censored competing risks data. Adopting the method of the pseudo-value estimator, this dissertation work proposes a novel approach to estimate the PE under the interval censored competing risks setting. Simulation studies are presented to assess performance of the MLR model and the PE in different scenarios. The proposed methods were then applied to a community-based study of cognitive impairment in aging population.

Public Health Significance: Interval-censored competing risks data could be often encountered in biomedical research that is essential for public health, such as rehabilitation and pain medicine. The proposed methods provide precise yet flexible modeling of such data with straightforward interpretation on how predictors affect the CIF, as well as useful tools to evaluate and validate the prediction accuracy of the developed models.

 

Last Updated On Monday, November 20, 2017 by Valenti, Renee Nerozzi
Created On Tuesday, November 07, 2017

Previous

Tue 8/8/2017
Zhaowen Sun: Power and Sample Size Determinations in Dynamic Risk Prediction Biostatistics Dissertation Defense
Zhaowen Sun: Power and Sample Size Determinations in Dynamic Risk Prediction
Tue 8/8/2017 10:00AM - 12:00PM
Public Health 7139

Zhaowen Sun of the Department of Biostatistics defends her dissertation on "Power and Sample Size Determinations in Dynamic Risk Prediction".

Fri 7/28/2017
Yi Liu: Novel Test Procedures for Large-scale Bivariate Time-to-event Data on Single and... Biostatistics Dissertation Defense
Yi Liu: Novel Test Procedures for Large-scale Bivariate Time-to-event Data on Single and...
Fri 7/28/2017 1:00PM - 3:00PM
Public Health 7139

Yi Liu of the Department of Biostatistics defends her dissertation on "Novel Test Procedures for Large-scale Bivariate Time-to-event Data on Single and Gene-based Markers, with an Application to a Genetic Study of AMD Progression"

Tue 7/18/2017
Yimeng Liu: Efficient Estimation of the Quantile Residual Lifetime Using Auxiliary Covariates Biostatistics Dissertation Defense
Yimeng Liu: Efficient Estimation of the Quantile Residual Lifetime Using Auxiliary Covariates
Tue 7/18/2017 10:30AM - 1:00PM
Public Health A522

Alice Liu of the Department of Biostatistics defends her dissertation on "Efficient Estimation of the Quantile Residual Lifetime Using Auxiliary Covariates"
Mon 7/17/2017
Judah Abberbock: Usage of Surrogate Endpoints in the Design and Analysis of Clinical Trials Biostatistics Dissertation Defense
Judah Abberbock: Usage of Surrogate Endpoints in the Design and Analysis of Clinical Trials
Mon 7/17/2017 2:00PM - 4:00PM
Public Health 7139

Judah Abberbock of the Department of Biostatistics defends his dissertation on "Usage of Surrogate Endpoints in the Design and Analysis of Clinical Trials"
Fri 5/5/2017
Abraham Apfel: "A Stability Analysis of Sparse K-means" Biostatistics Dissertation Defense
Abraham Apfel: "A Stability Analysis of Sparse K-means"
Fri 5/5/2017 9:00AM - 11:00AM
Public Health 7139

Abraham Apfel of the Department of Biostatistics defends his dissertation on "A Stability Analysis of Sparse K-means"
Fri 4/14/2017
Chien-Wei Lin: "Power calculation and study design in RNA-Seq and Methyl-Seq" Biostatistics Dissertation Defense
Chien-Wei Lin: "Power calculation and study design in RNA-Seq and Methyl-Seq"
Fri 4/14/2017 3:00PM - 5:00PM
Public Health 7139

Chien-Wei Lin of the Department of Biostatistics defends his dissertation on "Power calculation and study design in RNA-Seq and Methyl-Seq"
Thu 4/13/2017
Yuvika Paliwal: "Generalized Linear Mixed Models for Analysis of Cross-correlated Binary Data in..." Biostatistics Dissertation Defense
Yuvika Paliwal: "Generalized Linear Mixed Models for Analysis of Cross-correlated Binary Data in..."
Thu 4/13/2017 10:00AM - 12:00PM
Public Health 4140

Yuvika Paliwal of the Department of Biostatistics defends her dissertation on "Generalized Linear Mixed Models for Analysis of Cross-correlated Binary Data in Multi-reader Studies of Diagnostic Imaging"
Mon 4/10/2017
Shannon Woolley: "Tests for Random Signs Censoring in Competing Risks" Biostatistics Dissertation Defense
Shannon Woolley: "Tests for Random Signs Censoring in Competing Risks"
Mon 4/10/2017 2:00PM - 4:00PM
Public Health 7139

Shannon Woolley of the Department of Biostatistics defends her dissertation on "Tests for Random Signs Censoring in Competing Risks"

Wed 4/5/2017
Lauren Balmert: "Nonparametric and Semiparametric Inference on Quantile Lost Lifespan" Biostatistics Dissertation Defense
Lauren Balmert: "Nonparametric and Semiparametric Inference on Quantile Lost Lifespan"
Wed 4/5/2017 12:00PM - 2:00PM
Public Health A216

Lauren Balmert of the Department of Biostatistics defends her dissertation on "Nonparametric and Semiparametric Inference on Quantile Lost Lifespan"
Thu 3/30/2017
Zhiguang Huo: "Statistical Integrative Omics Methods for Disease Subtype Discovery" Biostatistics Dissertation Defense
Zhiguang Huo: "Statistical Integrative Omics Methods for Disease Subtype Discovery"
Thu 3/30/2017 1:00PM - 3:00PM
Public Health 7139


Zhiguang Huo of the Department of Biostatistics defends his dissertation on "Statistical Integrative Omics Methods for Disease Subtype Discovery"
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Questions and Submissions

The schedule of dissertation defenses in the Department of Biostatistics is maintained by:

Renee Valenti

412-624-3023

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